Product Name
protocadherin 19 (PCDH19), ELISA Kit
Full Product Name
Human Protocadherin-19, PCDH19 ELISA Kit
Product Synonym Names
Human Protocadherin-19 (PCDH19) ELISA kit; RP11-99E24.1; DKFZp686P1843; EFMR; KIAA1313; epilepsy; female restricted; with mental retardation (Juberg-Hellman syndrome) ; protocadherin 19
Product Gene Name
PCDH19 elisa kit
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q8TAB3
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of PCDH19 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for PCDH19 purchase
MBS9335831 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the protocadherin 19 (PCDH19) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PCDH19. The ELISA analytical biochemical technique of the MBS9335831 kit is based on PCDH19 antibody-PCDH19 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PCDH19 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PCDH19. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for PCDH19. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001098713.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001105243.1
[Other Products]
UniProt Primary Accession #
Q8TAB3
[Other Products]
UniProt Secondary Accession #
Q5JTG1; Q5JTG2; Q68DT7; Q9P2N3; B0LDS4; E9PAM6[Other Products]
UniProt Related Accession #
Q8TAB3[Other Products]
Molecular Weight
126,253 Da
NCBI Official Full Name
protocadherin-19 isoform a
NCBI Official Synonym Full Names
protocadherin 19
NCBI Official Symbol
PCDH19??[Similar Products]
NCBI Official Synonym Symbols
EFMR; EIEE9
??[Similar Products]
NCBI Protein Information
protocadherin-19
UniProt Protein Name
Protocadherin-19
Protein Family
Protocadherin
UniProt Gene Name
PCDH19??[Similar Products]
UniProt Synonym Gene Names
KIAA1313??[Similar Products]
UniProt Entry Name
PCD19_HUMAN
NCBI Summary for PCDH19
The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
UniProt Comments for PCDH19
PCDH19: Potential calcium-dependent cell-adhesion protein. Defects in PCDH19 are the cause of epileptic encephalopathy early infantile type 9 (EIEE9); also known as epilepsy female-restricted with mental retardation. A condition characterized by seizure with onset in infancy or early childhood, cognitive impairment, and delayed development of variable severity in some patients. Additional features include autistic signs and psychosis. The disorder is sex-limited, with the phenotype being restricted to females. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: Xq22.1
Cellular Component: integral to membrane; plasma membrane
Molecular Function: calcium ion binding
Biological Process: homophilic cell adhesion
Disease: Epileptic Encephalopathy, Early Infantile, 9
Research Articles on PCDH19
1. This study highlighted the significance of PCDH19 deletion, a unique pattern of initial seizure clusters, and the efficacy of antiepileptic drugs
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
