Full Product Name
DCTN4, NT (DCTN4, Dynactin subunit 4, Dynactin subunit p62)
Product Synonym Names
Anti -DCTN4, NT (DCTN4, Dynactin subunit 4, Dynactin subunit p62)
Product Gene Name
anti-DCTN4 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 5; NC_000005.9 (150088309..150138657, complement). Location: 5q31-q32
3D Structure
ModBase 3D Structure for Q9UJW0
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Immunogen
DCTN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DCTN4.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-DCTN4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DCTN4 antibody
DCTN4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
Product Categories/Family for anti-DCTN4 antibody
Antibodies; Abs to Proteins
Applications Tested/Suitable for anti-DCTN4 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-DCTN4 antibody
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
NCBI/Uniprot data below describe general gene information for DCTN4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001129116.1
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NCBI GenBank Nucleotide #
NM_001135644.1
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UniProt Primary Accession #
Q9UJW0
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UniProt Secondary Accession #
Q8TAN8; B3KWW0; D3DQH0; E5RGT5[Other Products]
UniProt Related Accession #
Q9UJW0[Other Products]
Molecular Weight
52,337 Da[Similar Products]
NCBI Official Full Name
dynactin subunit 4 isoform c
NCBI Official Synonym Full Names
dynactin 4 (p62)
NCBI Official Symbol
DCTN4??[Similar Products]
NCBI Official Synonym Symbols
P62; DYN4
??[Similar Products]
NCBI Protein Information
dynactin subunit 4; dynactin p62 subunit; dynactin subunit p62
UniProt Protein Name
Dynactin subunit 4
UniProt Synonym Protein Names
Dynactin subunit p62
UniProt Gene Name
DCTN4??[Similar Products]
UniProt Synonym Gene Names
Dyn4??[Similar Products]
UniProt Entry Name
DCTN4_HUMAN
UniProt Comments for DCTN4
dynactin 4: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Belongs to the dynactin subunit 4 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: 5q33.1
Cellular Component: centrosome; dynactin complex; cytoplasmic dynein complex; cytoplasm; nucleus; cytosol
Molecular Function: protein N-terminus binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; nuclear migration
Research Articles on DCTN4
1. used an extreme phenotype study to discover that variants in DCTN4, encoding a dynactin protein, are associated with time to first P. aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
