Product Name
DCTN4, cDNA Clone
Full Product Name
DCTN4 cDNA Clone
Product Gene Name
DCTN4 cdna clone
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcgtcct tgctgcagtc ggaccgggtt ctctatctag tccagggaga aaagaaggtt cgggccccgc tctcgcaact ctacttctgc cgctattgta gcgaactgcg gtcgctggaa tgtgtgtctc acgaggtgga ctcccattat tgtcccagtt gtttagaaaa tatgccatcg gctgaagcca aactaaaaaa gaatagatgt gccaattgtt ttgactgtcc tggctgcatg cacaccctct ctactcgggc cacgagcatc tccacacagc ttacagatga cccagccaag accaccatga agaaagccta ttacctggca tgtggatttt gtcgctggac gtctagagat gtgggcatgg cagacaaatc tgtagctagt ggcggttggc aggaacctga aaatcctcac acacaacgga tgaacaaatt gattgaatat taccagcagc ttgctcagaa agagaaggtt gagcgagatc gcaagaaact ggcacgacgt agaaactata tgcctctggc tttttcggac aaatatggtc ttggaaccag gcttcagcga ccacgagctg gtgcatccat cagtaccctt gccggacttt cccttaaaga aggagaggat cagaaagaga taaagattga gccagctcag gctgtggatg aagtggaacc tctacctgaa gactattata caagaccagt aaatttaaca gaggtaacaa cccttcagca gcgtctgtta cagcctgact tccagccagt ctgtgcttca cagctctatc ctcgccacaa acatcttctg atcaaacggt ccctgcgctg ccgtaaatgt gaacataatt tgagcaagcc agaatttaac ccaacgtcaa tcaaattcaa aatccagctg gtcgctgtca attatattcc agaagtgaga atcatgtcaa ttcccaacct tcgctacatg aaggagagcc aggtcctcct gactcttaca aatccagttg agaacctcac ccatgtgact ctattcgagt gtgaggaggg ggaccctgat gatatcaaca gcactgctaa ggtggtggtg cctcccaaag agctcgtttt agctggcaag gatgcagcag cagagtacga tgagttggca gaacctcaag actttcagga cgatcctgac attatagcct tcagaaaggc caacaaagtg ggtattttca tcaaagttac accacagcgt gaggagggtg aagtgaccgt gtgcttcaag atgaagcatg attttaaaaa cctggcagcc cccattcgcc ccattgaaga aagtgaccag ggaacagaag tcatctggct cacccagcat gtggaactta gcttgggccc acttcttcct taa
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of DCTN4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for DCTN4. It may not necessarily be applicable to this product.
NCBI Accession #
BC026323
[Other Products]
UniProt Secondary Accession #
Q8TAN8; B3KWW0; D3DQH0; E5RGT5[Other Products]
UniProt Related Accession #
Q9UJW0[Other Products]
Molecular Weight
53,152 Da
NCBI Official Full Name
Homo sapiens dynactin 4 (p62), mRNA
NCBI Official Synonym Full Names
dynactin subunit 4
NCBI Official Symbol
DCTN4??[Similar Products]
NCBI Official Synonym Symbols
P62; DYN4
??[Similar Products]
NCBI Protein Information
dynactin subunit 4
UniProt Protein Name
Dynactin subunit 4
UniProt Synonym Protein Names
Dynactin subunit p62
UniProt Gene Name
DCTN4??[Similar Products]
UniProt Synonym Gene Names
Dyn4??[Similar Products]
UniProt Entry Name
DCTN4_HUMAN
UniProt Comments for DCTN4
dynactin 4: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Belongs to the dynactin subunit 4 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motor; Motility/polarity/chemotaxis; Microtubule-binding
Chromosomal Location of Human Ortholog: 5q33.1
Cellular Component: centrosome; cytoplasm; cytoplasmic dynein complex; cytosol; dynactin complex; nucleus
Molecular Function: protein binding; protein N-terminus binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; ER to Golgi vesicle-mediated transport; nuclear migration
Research Articles on DCTN4
1. used an extreme phenotype study to discover that variants in DCTN4, encoding a dynactin protein, are associated with time to first P. aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis
Precautions
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Disclaimer
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