Full Product Name
CCNY Polyclonal Antibody
Product Synonym Names
Cyclin-Y; Cyc-Y; Cyclin box protein 1; Cyclin fold protein 1; cyclin-X; CCNY; C10orf9; CBCP1; CFP1
Product Gene Name
anti-CCNY antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8ND76
Species Reactivity
Human, Mouse
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Immunogen
Synthesized peptide derived from human protein. at AA range: 270-350
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-CCNY antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CCNY antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CCNY antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for CCNY. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001269781.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001282852.1
[Other Products]
UniProt Primary Accession #
Q8ND76
[Other Products]
UniProt Secondary Accession #
Q2M3V4; Q2TU96; Q6NT86; Q7Z4U7; Q8TEX2; Q8TEX3; Q96M99; Q96P45; B7ZKX9; D3DRY9[Other Products]
UniProt Related Accession #
Q8ND76[Other Products]
NCBI Official Full Name
cyclin-Y isoform 3
NCBI Official Synonym Full Names
cyclin Y
NCBI Official Symbol
CCNY??[Similar Products]
NCBI Official Synonym Symbols
CCNX; CFP1; CBCP1; C10orf9
??[Similar Products]
NCBI Protein Information
cyclin-Y
UniProt Protein Name
Cyclin-Y
UniProt Synonym Protein Names
Cyclin box protein 1; Cyclin fold protein 1; cyclin-X
UniProt Gene Name
CCNY??[Similar Products]
UniProt Synonym Gene Names
C10orf9; CBCP1; CFP1; Cyc-Y??[Similar Products]
NCBI Summary for CCNY
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009]
UniProt Comments for CCNY
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Research Articles on CCNY
1. findings revealed an unrecognized role of Caprin-2 in facilitating LRP5/6 constitutive phosphorylation at G2/M through forming a quaternary complex with CDK14, Cyclin Y, and LRP5/6.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
