Product Name
Metalloreductase STEAP3 (Steap3), Recombinant Protein
Full Product Name
Recombinant Mouse Metalloreductase STEAP3 (Steap3), partial
Product Gene Name
Steap3 recombinant protein
[Similar Products]
Product Synonym Gene Name
Steap3[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8CI59
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mus musculus (Mouse)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Steap3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Steap3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001078878.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001085409.1
[Other Products]
UniProt Primary Accession #
Q8CI59
[Other Products]
UniProt Secondary Accession #
Q3TKE4; Q80ZF3; Q8C5F0; Q924Z1[Other Products]
UniProt Related Accession #
Q8CI59[Other Products]
Molecular Weight
58,530 Da
NCBI Official Full Name
metalloreductase STEAP3
NCBI Official Synonym Full Names
STEAP family member 3
NCBI Official Symbol
Steap3??[Similar Products]
NCBI Official Synonym Symbols
Tsap6; pHyde; 1010001D01Rik
??[Similar Products]
NCBI Protein Information
metalloreductase STEAP3
UniProt Protein Name
Metalloreductase STEAP3
UniProt Synonym Protein Names
Dudulin-2; Protein nm1054; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6
Protein Family
Metalloreductase
UniProt Gene Name
Steap3??[Similar Products]
UniProt Synonym Gene Names
Tsap6??[Similar Products]
UniProt Comments for Steap3
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Also mediates reduction of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Research Articles on Steap3
1. TSAP6 deficiency results in abnormal erythroid maturation and leads to microcytic anemia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
