Product Name
High Density Lipoprotein Binding Protein (HDLBP), Polyclonal Antibody
Full Product Name
Biotin-Linked Polyclonal Antibody to High Density Lipoprotein Binding Protein (HDLBP)
Product Synonym Names
HBP; VGL; Vigilin
Product Gene Name
anti-HDLBP antibody
[Similar Products]
Matching Pairs
Unconjugated Antibody: High Density Lipoprotein (MBS2026662)
Biotin Conjugated Antibody: High Density Lipoprotein Binding Protein (HDLBP) (MBS2094615)
Matching Pairs
Biotin Conjugated Antibody: High Density Lipoprotein Binding Protein (HDLBP) (MBS2094615)
Immunogen: High Density Lipoprotein (MBS2031142)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Concentration
200ug/ml (lot specific)
Immunogen
HDLBP (Pro158~Ala371)
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Other Notes
Small volumes of anti-HDLBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-HDLBP antibody
Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for HDLBP. It may not necessarily be applicable to this product.
NCBI Accession #
AAH01179.1
[Other Products]
UniProt Secondary Accession #
Q53QU2; Q9UCY3; B4DTQ2; E7EM71[Other Products]
UniProt Related Accession #
Q00341[Other Products]
Molecular Weight
137,987 Da
NCBI Official Full Name
High density lipoprotein binding protein
NCBI Official Synonym Full Names
high density lipoprotein binding protein
NCBI Official Symbol
HDLBP??[Similar Products]
NCBI Official Synonym Symbols
HBP; VGL; PRO2900
??[Similar Products]
NCBI Protein Information
vigilin
UniProt Protein Name
Vigilin
UniProt Synonym Protein Names
High density lipoprotein-binding protein; HDL-binding protein
UniProt Gene Name
HDLBP??[Similar Products]
UniProt Synonym Gene Names
HBP; VGL; HDL-binding protein??[Similar Products]
NCBI Summary for HDLBP
The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation. [provided by RefSeq, Mar 2016]
UniProt Comments for HDLBP
vigilin: a nuclear and cytoplasmic protein that may play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.
Protein type: Lipid-binding; RNA-binding
Chromosomal Location of Human Ortholog: 2q37.3
Cellular Component: cytosol; high-density lipoprotein particle; nucleus; plasma membrane
Molecular Function: cadherin binding; lipid binding; protein binding; RNA binding
Biological Process: cholesterol metabolic process; high-density lipoprotein particle clearance; lipid transport
Research Articles on HDLBP
1. this study shows that vigilin (HDLBP) binds and negatively regulates MICB expression through its 5'UTR, and that vigilin downregulation in target cells leads to NK cell activation against said target cells
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.