Full Product Name
ASPA Rabbit Polyclonal
Product Gene Name
anti-ASPA antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS766877 Technical Datasheet
Technical Datasheet PDF
3D Structure
ModBase 3D Structure for Q6FH48
Species Reactivity
Human, Mouse, Rat
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Immunogen
Aspartoacylase (Canavan disease)
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ASPA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ASPA antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for ASPA. It may not necessarily be applicable to this product.
NCBI Accession #
CAG46706.1
[Other Products]
UniProt Primary Accession #
Q6FH48
[Other Products]
UniProt Related Accession #
P45381[Other Products]
Molecular Weight
35,735 Da
NCBI Official Full Name
ASPA, partial
NCBI Official Synonym Full Names
aspartoacylase
NCBI Official Symbol
ASPA??[Similar Products]
NCBI Official Synonym Symbols
ASP; ACY2
??[Similar Products]
NCBI Protein Information
aspartoacylase
UniProt Protein Name
ASPA protein
UniProt Synonym Protein Names
ASPA protein
Protein Family
Aspartocin
UniProt Gene Name
ASPA??[Similar Products]
UniProt Entry Name
Q6FH48_HUMAN
NCBI Summary for ASPA
This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Research Articles on ASPA
1. report of 2 Egyptian sibling patients suspected of Canavan disease (CD); study revealed homozygosity for substitution T530C (Ile177Thr) in exon 4 of the ASPA gene in both sibs; substitution T530C (Ile177Thr) results in a novel missense mutation causing a CD phenotype with severe clinical characteristics
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
