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Retinitis pigmentosa 9 protein (RP9), Recombinant Protein

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產(chǎn)品名稱: Retinitis pigmentosa 9 protein (RP9), Recombinant Protein
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簡單介紹

Retinitis pigmentosa 9 protein (RP9), Recombinant Protein


Retinitis pigmentosa 9 protein (RP9), Recombinant Protein  的詳細介紹
Product Name

Retinitis pigmentosa 9 protein (RP9), Recombinant Protein

Full Product Name

Recombinant Human Retinitis pigmentosa 9 protein (RP9)

Product Gene Name

RP9 recombinant protein

[Similar Products]
Product Synonym Gene Name
RP9[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence Positions
1-221aa, full length protein
Sequence
MSSRPGREDV GAAGARRPRE PPEQELQRRR EQKRRRHDAQ QLQQLKHLES FYEKPPPGLI KEDETKPEDC IPDVPGNEHA REFLAHAPTK GLWMPLGKEV KVMQCWRCKR YGHRTGDKEC PFFIKGNQKL EQFRVAHEDP MYDIIRDNKR HEKDVRIQQL KQLLEDSTSD EDRSSSSSSE GKEKHKKKKK KEKHKKRKKE KKKKKKRKHK SSKSNEGSDS E
OMIM
180104
3D Structure
ModBase 3D Structure for Q8TA86
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of RP9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
RP9 recombinant protein
This protein can be bound and phosphorylated by the protooncogene PIM1 product, a serine
threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene.
NCBI/Uniprot data below describe general gene information for RP9. It may not necessarily be applicable to this product.
NCBI GI #
42718020
NCBI GeneID
6100
NCBI Accession #
NP_976033.1 [Other Products]
NCBI GenBank Nucleotide #
NM_203288.1 [Other Products]
UniProt Primary Accession #
Q8TA86 [Other Products]
UniProt Related Accession #
Q8TA86[Other Products]
Molecular Weight
26,107 Da
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NCBI Official Full Name
retinitis pigmentosa 9 protein
NCBI Official Synonym Full Names
RP9, pre-mRNA splicing factor
NCBI Official Symbol
RP9??[Similar Products]
NCBI Official Synonym Symbols
PAP1; PAP-1
??[Similar Products]
NCBI Protein Information
retinitis pigmentosa 9 protein
UniProt Protein Name
Retinitis pigmentosa 9 protein
UniProt Synonym Protein Names
Pim-1-associated protein; PAP-1
Protein Family
Retinitis pigmentosa 9 protein
UniProt Gene Name
RP9??[Similar Products]
UniProt Synonym Gene Names
PAP-1??[Similar Products]
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NCBI Summary for RP9
The protein encoded by this gene can be bound and phosphorylated by the protooncogene PIM1 product, a serine/threonine protein kinase . This protein localizes in nuclear speckles containing the splicing factors, and has a role in pre-mRNA splicing. CBF1-interacting protein (CIR), a corepressor of CBF1, can also bind to this protein and effects alternative splicing. Mutations in this gene result in autosomal dominant retinitis pigmentosa-9. This gene has a pseudogene (GeneID: 441212), which is located in tandem array approximately 166 kb distal to this gene. [provided by RefSeq, Sep 2009]
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UniProt Comments for RP9
Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1 ().
Research Articles on RP9
1. Observational study of genetic testing. (HuGE Navigator)
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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