Full Product Name
INSRR Antibody
Product Synonym Names
INSRR; INSRR_HUMAN; Insulin receptor related receptor precursor; Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain; insulin receptor-related receptor; IR R; IR related receptor; IR-related receptor; IRR; Sir r; Sirr
Product Gene Name
anti-INSRR antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P14616
Specificity
INSRR Antibody detects endogenous levels of total INSRR
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
A synthesized peptide derived from human INSRR
Preparation and Storage
Store at-20 degree C. Stable for 12 months from date of receipt.
Other Notes
Small volumes of anti-INSRR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-INSRR antibody
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Applications Tested/Suitable for anti-INSRR antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-INSRR antibody
WB: 1:1000-3000
IHC: 1:200
IF/ICC: 1:200-1:500
Western Blot (WB) of anti-INSRR antibody
Western blot analysis INSRR using K562 whole cell lysates
NCBI/Uniprot data below describe general gene information for INSRR. It may not necessarily be applicable to this product.
NCBI Accession #
NP_055030.1
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NCBI GenBank Nucleotide #
NM_014215.2
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UniProt Primary Accession #
P14616
[Other Products]
UniProt Secondary Accession #
O60724; Q5VZS3[Other Products]
UniProt Related Accession #
P14616[Other Products]
NCBI Official Full Name
insulin receptor-related protein
NCBI Official Synonym Full Names
insulin receptor related receptor
NCBI Official Symbol
INSRR??[Similar Products]
NCBI Official Synonym Symbols
IRR
??[Similar Products]
NCBI Protein Information
insulin receptor-related protein
UniProt Protein Name
Insulin receptor-related protein
UniProt Synonym Protein Names
IR-related receptor
Protein Family
Insulin receptor-related protein
UniProt Gene Name
INSRR??[Similar Products]
UniProt Synonym Gene Names
IRR; IRR??[Similar Products]
UniProt Comments for INSRR
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Research Articles on INSRR
1. IRR activation involves two separate centers of pH-dependent rearrangements that act synergistically to induce a major conformational change in the IRR molecule, resulting in internal kinase domains rapprochement and autophosphorylation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
