Product Name
B-cell antigen receptor complex-associated protein alpha chain (CD79A), Recombinant Protein
Full Product Name
B-cell antigen receptor complex-associated protein alpha chain
Product Gene Name
CD79A recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
33-236aa; full length protein
Sequence
LWVDGGPPSM TVSLGETARL QCLHNRSRLS SKLNITWWRV LQGNATWPDI FLSYGKGPNG ELTIDTVNKS HMGMYRCQVE EKDLNQKILS SQQSCGTYLR VRERLPRPFL DMGEGTKNNI ITAEGIILLF CAVVPGTLLL FRKRWQNMKF GVDAQDDYED ENLYEGLNLD DCSMYEDISR GLQGTYQDVG SLHIGDGDVQ LEKP
3D Structure
ModBase 3D Structure for P0CAN6
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Species
Canis familiaris (Dog) (Canis lupus familiaris)
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CD79A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CD79A recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Product Categories/Family for CD79A recombinant protein
Transmembrane Protein
NCBI/Uniprot data below describe general gene information for CD79A. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001300763.1
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NCBI GenBank Nucleotide #
NM_001313834.1
[Other Products]
UniProt Primary Accession #
P0CAN6
[Other Products]
UniProt Related Accession #
P0CAN6[Other Products]
Molecular Weight
26,120 Da
NCBI Official Full Name
B-cell antigen receptor complex-associated protein alpha chain
NCBI Official Symbol
CD79A??[Similar Products]
NCBI Official Synonym Symbols
IG-alpha
??[Similar Products]
NCBI Protein Information
B-cell antigen receptor complex-associated protein alpha chain
UniProt Protein Name
B-cell antigen receptor complex-associated protein alpha chain
UniProt Synonym Protein Names
Ig-alpha; CD_antigen: CD79a
Protein Family
B-cell antigen receptor complex-associated protein
UniProt Gene Name
CD79A??[Similar Products]
UniProt Entry Name
CD79A_CANLF
UniProt Comments for CD79A
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells ().
Research Articles on CD79A
1. This study examined the immunoreactivity of a monoclonal antibody to MUM1/IRF4 and compared it with expression of CD79a and CD20 in 109 plasmacytomas in 107 dogs.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
