Product Name
Homeobox protein engrailed-1 (En1), Recombinant Protein
Full Product Name
Recombinant Mouse Homeobox protein engrailed-1 (En1)
Product Gene Name
En1 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-401aa, Full length protein
Sequence
MEEQQPEPKS QRDSGLGAVA AAAPSGLSLS LSPGASGSSG SDGDSVPVSP QPAPPSPPAA PCLPPLAHHP HLPPHPPPPP PPPPPPPQHL AAPAHQPQPA AQLHRTTNFF IDNILRPDFG CKKEQPLPQL LVASAAAGGG AAAGGGSRVE RDRGQTGAGR DPVHSLGTRA SGAASLLCAP DANCGPPDGS QPATAVSAGA SKAGNPAAAA AAAAAAAAAA VAAAAAAASK PSDSGGGSGG NAGSPGAQGA KFPEHNPAIL LMGSANGGPV VKTDSQQPLV WPAWVYCTRY SDRPSSGPRT RKLKKKKNEK EDKRPRTAFT AEQLQRLKAE FQANRYITEQ RRQTLAQELS LNESQIKIWF QNKRAKIKKA TGIKNGLALH LMAQGLYNHS TTTVQDKDES E
3D Structure
ModBase 3D Structure for P09065
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of En1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
En1 recombinant protein
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the engrailed (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
NCBI/Uniprot data below describe general gene information for En1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_034263.2
[Other Products]
NCBI GenBank Nucleotide #
NM_010133.2
[Other Products]
UniProt Primary Accession #
P09065
[Other Products]
UniProt Secondary Accession #
Q3USF7[Other Products]
UniProt Related Accession #
P09065[Other Products]
Molecular Weight
40,981 Da
NCBI Official Full Name
homeobox protein engrailed-1
NCBI Official Synonym Full Names
engrailed 1
NCBI Official Symbol
En1??[Similar Products]
NCBI Official Synonym Symbols
En-1; Mo-en.1; engrailed-1
??[Similar Products]
NCBI Protein Information
homeobox protein engrailed-1
UniProt Protein Name
Homeobox protein engrailed-1
Protein Family
Homeobox protein
UniProt Gene Name
En1??[Similar Products]
UniProt Synonym Gene Names
En-1; Homeobox protein en-1; Mo-En-1??[Similar Products]
Research Articles on En1
1. En1 is important for ventral nuclei of the lateral lemniscus neuron development and survival.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.