Human Neuronal acetylcholine receptor subunit alpha-9 (CHRNA9) ELISA kit; HSA243342; MGC142109; MGC142135; NACHRA9; NACHR alpha 9; acetylcholine receptor; neuronal nicotinic; alpha-9 subunit; cholinergic receptor; nicotinic; alpha polypeptide 9; neuronal acetylcholine recept; cholinergic receptor; nicotinic; alpha 9

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of CHRNA9 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9329072 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cholinergic receptor, nicotinic, alpha 9 (CHRNA9) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CHRNA9. The ELISA analytical biochemical technique of the MBS9329072 kit is based on CHRNA9 antibody-CHRNA9 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CHRNA9 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CHRNA9. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

54,807 Da

cholinergic receptor, nicotinic, alpha 9 (neuronal)

neuronal acetylcholine receptor subunit alpha-9; NACHR alpha 9; nicotinic acetylcholine receptor subunit alpha 9; cholinergic receptor, nicotinic, alpha polypeptide 9; neuronal acetylcholine receptor protein, alpha-9 subunit; acetylcholine receptor, neuronal nicotinic, alpha-9 subunit

Neuronal acetylcholine receptor subunit alpha-9

NACHRA9; NACHR alpha-9??[Similar Products]

ACHA9_HUMAN

This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the ***** cochlea. [provided by RefSeq, Feb 2012]

nAChRA9: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha- 9/CHRNA9 sub-subfamily.

Protein type: Membrane protein, integral; Channel, ligand-gated; Membrane protein, multi-pass; Channel, cation

Chromosomal Location of Human Ortholog: 4p14

Cellular Component: nicotinic acetylcholine-gated receptor-channel complex; postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction

Molecular Function: calcium channel activity; acetylcholine-gated cation channel activity; nicotinic acetylcholine-activated cation-selective channel activity

Biological Process: synaptic transmission; inner ear morphogenesis; elevation of cytosolic calcium ion concentration; detection of mechanical stimulus involved in sensory perception of sound

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