Full Product Name
ApoE Antibody
Product Synonym Names
Apo-E; Apolipoprotein E; APOE
Product Gene Name
anti-APOE antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P02649
Species Reactivity
Human, Mouse, Rat
Specificity
ApoE antibody detects endogenous levels of ApoE.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human ApoE.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-APOE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-APOE antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-APOE antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000
Western Blot (WB) of anti-APOE antibody
Western blot analysis of lysate from RAW264.7cells, using ApoE antibody.
Immunohistochemistry (IHC) of anti-APOE antibody
Immunohistochemistry analysis of ApoE antibody in paraffin-embedded human lung carcinoma tissue.
NCBI/Uniprot data below describe general gene information for APOE. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000032.1
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NCBI GenBank Nucleotide #
NM_000041.3
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UniProt Primary Accession #
P02649
[Other Products]
UniProt Secondary Accession #
Q9P2S4; B2RC15; C0JYY5[Other Products]
UniProt Related Accession #
P02649[Other Products]
NCBI Official Full Name
apolipoprotein E isoform b
NCBI Official Synonym Full Names
apolipoprotein E
NCBI Official Symbol
APOE??[Similar Products]
NCBI Official Synonym Symbols
AD2; LPG; APO-E; ApoE4; LDLCQ5
??[Similar Products]
NCBI Protein Information
apolipoprotein E
UniProt Protein Name
Apolipoprotein E
Protein Family
Apolipoprotein
UniProt Gene Name
APOE??[Similar Products]
UniProt Synonym Gene Names
Apo-E??[Similar Products]
NCBI Summary for APOE
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
UniProt Comments for APOE
Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
Research Articles on APOE
1. Apolipoprotein E epsilon 4 genotype status is not associated with neuroimaging outcomes in a large cohort of HIV-infected individuals.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
