Full Product Name
VCX Antibody
Product Synonym Names
VCX1; VCXB1; VCX-B1; VCX10R; VCX-10r
Product Gene Name
anti-VCX antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9H320
Specificity
The antibody detects endogenous levels of total VCX protein.
Purity/Purification
Antigen affinity purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.7mg/ml (lot specific)
Immunogen
Synthetic peptide of human VCX
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-VCX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-VCX antibody
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 10 repeats of the 30-bp unit.
Product Categories/Family for anti-VCX antibody
Total protein Ab
Applications Tested/Suitable for anti-VCX antibody
Immunohistochemistry (IHC)
Application Notes for anti-VCX antibody
Immunohistochemistry: 1: 20-100
Immunohistochemistry (IHC) of anti-VCX antibody
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using VCX Antibody at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)
NCBI/Uniprot data below describe general gene information for VCX. It may not necessarily be applicable to this product.
NCBI Accession #
NP_038480.2
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NCBI GenBank Nucleotide #
NM_013452.2
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UniProt Primary Accession #
Q9H320
[Other Products]
UniProt Secondary Accession #
Q4V774; Q9P0H3; A0JNS5[Other Products]
UniProt Related Accession #
Q9H320[Other Products]
Molecular Weight
22,289 Da
NCBI Official Full Name
variable charge X-linked protein 1
NCBI Official Synonym Full Names
variable charge, X-linked
NCBI Official Symbol
VCX??[Similar Products]
NCBI Official Synonym Symbols
VCX1; VCXB1; VCX-B1; VCX10R; VCX-10r
??[Similar Products]
NCBI Protein Information
variable charge X-linked protein 1
UniProt Protein Name
Variable charge X-linked protein 1
UniProt Synonym Protein Names
Variable charge protein on X with ten repeats; VCX-10r; Variably charged protein X-B1; VCX-B1
Protein Family
Variable charge X-linked protein
UniProt Gene Name
VCX??[Similar Products]
UniProt Synonym Gene Names
VCX1; VCX10R; VCXB1; VCX-10r; VCX-B1??[Similar Products]
UniProt Entry Name
VCX1_HUMAN
NCBI Summary for VCX
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 10 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008]
UniProt Comments for VCX
VCX: May mediate a process in spermatogenesis or may play a role in sex ratio distortion. Belongs to the VCX/VCY family.
Chromosomal Location of Human Ortholog: Xp22
Cellular Component: nucleolus; nucleus
Molecular Function: chromatin binding
Biological Process: brain development; establishment and/or maintenance of chromatin architecture; spermatogenesis
Research Articles on VCX
1. Identified members of the VCX/Y gene family as novel CT antigens.
Precautions
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Disclaimer
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