Product Name
nonhomologous end-joining factor 1 (NHEJ1), ELISA Kit
Full Product Name
Mouse Non-homologous end-joining factor 1, NHEJ1 ELISA Kit
Product Synonym Names
Mouse Non-homologous end-joining factor 1 (NHEJ1) ELISA kit; FLJ12610; XLF; Cernunnos; XRCC4-like factor; nonhomologous end-joining factor 1
Product Gene Name
NHEJ1 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q3KNJ2
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of NHEJ1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for NHEJ1 purchase
MBS9323804 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the nonhomologous end-joining factor 1 (NHEJ1) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NHEJ1. The ELISA analytical biochemical technique of the MBS9323804 kit is based on NHEJ1 antibody-NHEJ1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NHEJ1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NHEJ1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for NHEJ1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_083618.3
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NCBI GenBank Nucleotide #
NM_029342.4
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UniProt Primary Accession #
Q3KNJ2
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UniProt Secondary Accession #
Q99JK0; Q9D9U0; A2RT39[Other Products]
UniProt Related Accession #
Q3KNJ2[Other Products]
Molecular Weight
32,739 Da
NCBI Official Full Name
non-homologous end-joining factor 1
NCBI Official Synonym Full Names
nonhomologous end-joining factor 1
NCBI Official Symbol
Nhej1??[Similar Products]
NCBI Official Synonym Symbols
XLF; cernunnos; 1700029B21Rik
??[Similar Products]
NCBI Protein Information
non-homologous end-joining factor 1; XRCC4-like factor; protein cernunnos
UniProt Protein Name
Non-homologous end-joining factor 1
UniProt Synonym Protein Names
Protein cernunnos; XRCC4-like factor
Protein Family
Non-homologous end-joining factor
UniProt Gene Name
Nhej1??[Similar Products]
UniProt Synonym Gene Names
Xlf??[Similar Products]
UniProt Entry Name
NHEJ1_MOUSE
UniProt Comments for NHEJ1
NHEJ1: DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary. Interacts with XRCC4 and the XRCC4-LIG4 complex. Binds DNA in a length-dependent manner. Ubiquitously expressed. Belongs to the XLF family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA repair, damage
Cellular Component: nucleus
Molecular Function: DNA binding
Biological Process: double-strand break repair; B cell differentiation; response to ionizing radiation; DNA repair; response to DNA damage stimulus; double-strand break repair via nonhomologous end joining; DNA recombination; T cell differentiation
Research Articles on NHEJ1
1. XLF functionally overlaps with DNA-PKcs in normal development, promotion of genomic stability in fibroblasts, and in IgH class switch recombination in mature B cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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