Product Name
CABP4, Blocking Peptide
Full Product Name
CABP4 Blocking Peptide
Product Synonym Names
Calcium-binding protein 4; CaBP4
Product Gene Name
CABP4 blocking peptide
[Similar Products]
CABP4 peptide (MBS822749) is used for blocking the activity of CABP4 antibody (MBS821777)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P57796
Species Reactivity
Human, Mouse, Rat, Bovine, Monkey
Form/Format
Lyophilized powder
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Other Notes
Small volumes of CABP4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CABP4 blocking peptide
The peptide is used to block Anti-CABP4 Antibody reactivity.
Applications Tested/Suitable for CABP4 blocking peptide
Blocking (BL)
Application Notes for CABP4 blocking peptide
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
NCBI/Uniprot data below describe general gene information for CABP4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001287824.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001300895.1
[Other Products]
UniProt Primary Accession #
P57796
[Other Products]
UniProt Secondary Accession #
Q8N4Z2; Q8WWY5[Other Products]
UniProt Related Accession #
P57796[Other Products]
Molecular Weight
19,600 Da
NCBI Official Full Name
calcium-binding protein 4 isoform b
NCBI Official Synonym Full Names
calcium binding protein 4
NCBI Official Symbol
CABP4??[Similar Products]
NCBI Official Synonym Symbols
CSNB2B
??[Similar Products]
NCBI Protein Information
calcium-binding protein 4
UniProt Protein Name
Calcium-binding protein 4
Protein Family
Calcium-binding protein
UniProt Gene Name
CABP4??[Similar Products]
UniProt Synonym Gene Names
CaBP4??[Similar Products]
UniProt Entry Name
CABP4_HUMAN
NCBI Summary for CABP4
This gene encodes a member of the CABP family of calcium binding protein characterized by four EF-hand motifs. Mutations in this gene are associated with congenital stationary night blindness type 2B. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
UniProt Comments for CABP4
CABP4: Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages. Defects in CABP4 are the cause of congenital stationary night blindness type 2B (CSNB2B). Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Calcium-binding
Chromosomal Location of Human Ortholog: 11q13.2
Cellular Component: extracellular region; terminal button; synapse; cytosol
Molecular Function: calcium ion binding
Biological Process: retinal cone cell development; visual perception; phototransduction; photoreceptor cell morphogenesis; signal transduction; retinal bipolar neuron differentiation
Disease: Night Blindness, Congenital Stationary, Type 2b
Research Articles on CABP4
1. we found a homozygous compound mutation in the CABP4 gene in 3 patients with congenital stationary night blindess 2.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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