Product Name
CACNB2, Blocking Peptide
Full Product Name
CACNB2 Peptide
Product Gene Name
CACNB2 blocking peptide
[Similar Products]
Product Synonym Gene Name
RP11-383B4.2; CACNLB2; FLJ23743; MYSB; CAVB2[Similar Products]
CACNB2 peptide (MBS3227633) is used for blocking the activity of CACNB2 antibody (MBS3202654)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q5VWD7
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of CACNB2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CACNB2 blocking peptide
This is a synthetic peptide designed for use in combination with anti-CACNB2 antibody made
Target Description: CACNB2 is a subunit of voltage-dependent calcium (Ca2+) channels, expressed in the CNS. It appears to serve an obligatory function.
Product Categories/Family for CACNB2 blocking peptide
Peptide
Applications Tested/Suitable for CACNB2 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for CACNB2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000715
[Other Products]
NCBI GenBank Nucleotide #
NM_000724
[Other Products]
UniProt Primary Accession #
Q5VWD7
[Other Products]
UniProt Related Accession #
Q08289[Other Products]
NCBI Official Full Name
voltage-dependent L-type calcium channel subunit beta-2 isoform 1
NCBI Official Synonym Full Names
calcium voltage-gated channel auxiliary subunit beta 2
NCBI Official Symbol
CACNB2??[Similar Products]
NCBI Official Synonym Symbols
MYSB; CAVB2; CACNLB2
??[Similar Products]
NCBI Protein Information
voltage-dependent L-type calcium channel subunit beta-2
Protein Family
Voltage-dependent L-type calcium channel
NCBI Summary for CACNB2
This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]
Research Articles on CACNB2
1. Data show that an indispensable beta-subunit of the voltage-gated Ca(2+) channel Cav1.2 interaction with H-Ras is independently of Ca(2+) flux, suggesting the regulatory role of beta2 in transcriptional activation via the ERK/CREB pathway.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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