Product Name
hyaluronidase 1 (HYAL1), Blocking Peptide
Full Product Name
hyaluronidase 1 Immunizing Peptide
Product Synonym Names
hyaluronoglucosaminidase 1; Hyal; Hyal-1; hyaluronidase 1; Hyaluronidase 1; hyaluronidase 1 (mouse, rat)
Product Gene Name
HYAL1 blocking peptide
[Similar Products]
hyaluronidase 1 peptide (MBS425367) is used for blocking the activity of hyaluronidase 1 antibody (MBS420656)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Mouse, Rat
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of HYAL1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for HYAL1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_032343.2
[Other Products]
NCBI GenBank Nucleotide #
NM_008317.4
[Other Products]
UniProt Secondary Accession #
O70229; Q8CE62; Q8QZX3; Q8VBW7; Q8VDK0; B1AV90[Other Products]
UniProt Related Accession #
Q91ZJ9[Other Products]
Molecular Weight
51,436 Da
NCBI Official Full Name
hyaluronidase-1
NCBI Official Synonym Full Names
hyaluronoglucosaminidase 1
NCBI Official Symbol
Hyal1??[Similar Products]
NCBI Official Synonym Symbols
Hya1; Hyal-1
??[Similar Products]
NCBI Protein Information
hyaluronidase-1
UniProt Protein Name
Hyaluronidase-1
UniProt Synonym Protein Names
Hyaluronoglucosaminidase-1
Protein Family
Hyaluronidase
UniProt Gene Name
Hyal1??[Similar Products]
UniProt Synonym Gene Names
Hyal-1??[Similar Products]
UniProt Entry Name
HYAL1_MOUSE
UniProt Comments for HYAL1
HYAL1: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth. Defects in HYAL1 are the cause of mucopolysaccharidosis type 9 (MPS9); also called hyaluronidase deficiency. MPS9 is a lysosomal storage disease characterized by high hyaluronan (HA) concentration in the serum. The clinical features are periarticular soft tissue masses, mild short stature and acetabular erosions, and absence of neurological or visceral involvement. Belongs to the glycosyl hydrolase 56 family. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; Secreted; Secreted, signal peptide; Glycan Metabolism - glycosaminoglycan degradation; EC 3.2.1.35
Cellular Component: cytoplasm; cytoplasmic vesicle; extracellular region; extracellular space; lysosome
Molecular Function: catalytic activity; hyaluronan synthase activity; hyalurononglucosaminidase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; transcription factor binding; viral receptor activity
Biological Process: carbohydrate metabolic process; hyaluronan biosynthetic process; hyaluronan catabolic process; hyaluronan metabolic process; inflammatory response; metabolic process; negative regulation of cell growth; positive regulation of angiogenesis; positive regulation of cell adhesion; positive regulation of cell growth; positive regulation of epithelial cell proliferation; positive regulation of growth; response to antibiotic; response to reactive oxygen species; response to virus
Research Articles on HYAL1
1. HYAL1 is necessary for the breakdown of intracellular HA in the cortex, whereas HYAL2 is essential for the degradation of extracellular HA in all kidney regions
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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