Product Name
PIP5KI gamma (Pip5k1c), Polyclonal Antibody
Full Product Name
PIP5KI gamma, NT (Phosphatidylinositol-4-phosphate 5-kinase, Type I, gamma, PtdIns(4)P-5-kinase 1 gamma, Phosphatidylinositol-4-phosphate 5-kinase Type I gamma, PIP5KIgamma, PIP5K1C, KIAA0589)
Product Synonym Names
Anti -PIP5KI gamma, NT (Phosphatidylinositol-4-phosphate 5-kinase, Type I, gamma, PtdIns(4)P-5-kinase 1 gamma, Phosphatidylinositol-4-phosphate 5-kinase Type I gamma, PIP5KIgamma, PIP5K1C, KIAA0589)
Product Gene Name
anti-Pip5k1c antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 10; NC_000076.6 (81292972..81319974). Location: 10 C1; 10
3D Structure
ModBase 3D Structure for O70161
Specificity
Recognizes human PIP5K1G.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.09% sodium azide.
Immunogen
Synthetic peptide selected from the N-terminal region of human PIP5K1G (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-Pip5k1c antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Pip5k1c antibody
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Product Categories/Family for anti-Pip5k1c antibody
Antibodies; Abs to Protein Kinases
Applications Tested/Suitable for anti-Pip5k1c antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-Pip5k1c antibody
Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
NCBI/Uniprot data below describe general gene information for Pip5k1c. It may not necessarily be applicable to this product.
NCBI Accession #
O70161.2
[Other Products]
UniProt Primary Accession #
O70161
[Other Products]
UniProt Secondary Accession #
Q505A1; Q80TW9; Q8VCU5[Other Products]
UniProt Related Accession #
O70161[Other Products]
Molecular Weight
72,408 Da[Similar Products]
NCBI Official Full Name
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
NCBI Official Synonym Full Names
phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
NCBI Official Symbol
Pip5k1c??[Similar Products]
NCBI Official Synonym Symbols
AI115456; AI835305; Pip5kIgamma
??[Similar Products]
NCBI Protein Information
phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; PIP5K1-gamma; ptdIns(4)P-5-kinase 1 gamma; phosphatidylinositol 4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
UniProt Protein Name
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
UniProt Synonym Protein Names
Phosphatidylinositol 4-phosphate 5-kinase type I gamma
Protein Family
Phosphatidylinositol 4-phosphate 5-kinase
UniProt Gene Name
Pip5k1c??[Similar Products]
UniProt Synonym Gene Names
Kiaa0589; PIP5K1-gamma; PtdIns(4)P-5-kinase 1 gamma; PIP5KIgamma??[Similar Products]
UniProt Entry Name
PI51C_MOUSE
UniProt Comments for Pip5k1c
PIP5K1C: a member of the type I phosphatidylinositol-4-phosphate 5-kinase family of enzymes. A similar protein in mice is found in synapses and focal adhesion plaques, and binds the FERM domain of talin through its C-terminus.
Protein type: Motility/polarity/chemotaxis; Kinase, lipid; Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.68
Cellular Component: cell projection; membrane; cell; cytoplasm; plasma membrane; cell junction
Molecular Function: transferase activity; protein binding; phosphatidylinositol phosphate kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; nucleotide binding; kinase activity; ATP binding
Biological Process: exocytosis; axonogenesis; cytoskeletal anchoring; phosphoinositide phosphorylation; endocytosis; phosphatidylinositol metabolic process; cell adhesion; chemotaxis; phosphorylation; phagocytosis
Research Articles on Pip5k1c
1. Although PIP5KIgamma is essential for normal platelet function, individual isoforms of PIP5KIgamma fulfill unique roles for the integrin-dependent integrity of the membrane cytoskeleton and for the stabilization of platelet adhesion.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.