For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of HTR2B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9380948 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 5-Hydroxytryptamine Receptor 2B (HTR2B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HTR2B. The ELISA analytical biochemical technique of the MBS9380948 kit is based on HTR2B antibody-HTR2B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HTR2B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HTR2B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

53,652 Da

5-hydroxytryptamine receptor 2B

5-hydroxytryptamine receptor 2B

5-hydroxytryptamine receptor 2B

Srl; 5-HT-2B; 5-HT2B??[Similar Products]

5HT2B_RAT

G-protein coupled receptor for serotonin [RGD, Feb 2006]

5-HT(2B): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Cellular Component: cell soma; cytoplasm; dendrite; membrane; plasma membrane

Molecular Function: drug binding; G-protein alpha-subunit binding; GTPase activator activity; protein binding; serotonin binding; serotonin receptor activity

Biological Process: calcium-mediated signaling; cellular calcium ion homeostasis; cGMP biosynthetic process; embryonic morphogenesis; G-protein coupled receptor internalization; G-protein coupled receptor protein signaling pathway; heart development; heart morphogenesis; inositol phosphate metabolic process; intestine smooth muscle contraction; negative regulation of apoptosis; negative regulation of autophagy; neural crest cell differentiation; neural crest cell migration; phosphoinositide 3-kinase cascade; phospholipase C activation; phosphorylation; positive regulation of cell division; positive regulation of cell proliferation; positive regulation of cytokine production; positive regulation of cytokine secretion; positive regulation of endothelial cell proliferation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of MAP kinase activity; positive regulation of nitric-oxide synthase activity; positive regulation of phosphatidylinositol biosynthetic process; protein kinase C activation; regulation of behavior; release of sequestered calcium ion into cytosol; response to drug; serotonin receptor signaling pathway; vasoconstriction

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