Product Name
Aspartate--tRNA ligase, mitochondrial (Dars2), Recombinant Protein
Full Product Name
Recombinant Rat Aspartate--tRNA ligase, mitochondrial (Dars2)
Product Gene Name
Dars2 recombinant protein
[Similar Products]
Product Synonym Gene Name
Dars2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
47-652aa, Full Length of Mature Protein
Sequence
VARTNTCGEL RSSHLGQEVT LCGWIQYRRQ NTFLVLRDCH GLVQILIPQD ESAASVRRTL CEAPVESVVR VSGTVIARPL GQENPKMPTG EIEIKAKTAE LLNACKKLPF EIKDFVKKTE ALRLQYRYLD LRSSQMQHNL RLRSQMVMKM REYLCTLHGF VDIETPTLFK RTPGGAKEFL VPSREPGRFY SLPQSPQQFK QLLMVGGLDR YFQVARCYRD EGSRPDRQPE FTQIDIEMSF VDQTGIQHLV EGLLHYSWPE DKDPLVAPFP SMTFAEALAT YGTDKPDTRF GMKIVDISDV FRNTEIRFLQ DALAKPQGTV KAICVHEGAK YLRKEDIEFI RKFAAHHFSQ EVLPIFLNAR KNWSSPFAKF ITEEERLELT RLMEIQEDDM VLLTAGQHEK ACSLLGKLRL ECADLLETRG LALRDPALFS FLWVLDFPLF LAKEESPTEL ESAHHPFTAP HPGDIHLLYT EPEKVRGQHY DLVLNGNEIG GGSIRIHDAQ LQRYILETLL KEDVKLLSHL LQALDYGAPP HGGIALGLDR LVCLVTGAPS IRDVIAFPKS YRGHDLMSNA PDTVSPEDLK PYHIHVSWPT DSEERASATP SKYLSS
3D Structure
ModBase 3D Structure for Q3KRD0
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Dars2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Dars2 recombinant protein
This protein belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).
NCBI/Uniprot data below describe general gene information for Dars2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001029315.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001034143.1
[Other Products]
UniProt Primary Accession #
Q3KRD0
[Other Products]
UniProt Related Accession #
Q3KRD0[Other Products]
Molecular Weight
73,953 Da
NCBI Official Full Name
aspartate--tRNA ligase, mitochondrial
NCBI Official Synonym Full Names
aspartyl-tRNA synthetase 2 (mitochondrial)
NCBI Official Symbol
Dars2??[Similar Products]
NCBI Official Synonym Symbols
RGD1308286
??[Similar Products]
NCBI Protein Information
aspartate--tRNA ligase, mitochondrial
UniProt Protein Name
Aspartate--tRNA ligase, mitochondrial
UniProt Synonym Protein Names
Aspartyl-tRNA synthetase; AspRS
UniProt Gene Name
Dars2??[Similar Products]
UniProt Synonym Gene Names
AspRS??[Similar Products]
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
