Product Name
Agouti-signaling protein (ASIP), Recombinant Protein
Full Product Name
Recombinant Bovine Agouti-signaling protein (ASIP)
Product Synonym Names
Agouti switch protein
Product Gene Name
ASIP recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
Full Length, 23-133aa
3D Structure
ModBase 3D Structure for Q29414
Species Reactivity
Bovine
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Tris-based buffer, 50% glycerol
Tag Info
N-terminal 6xHis-SUMO-tagged
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Other Notes
Small volumes of ASIP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ASIP recombinant protein
Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment).
NCBI/Uniprot data below describe general gene information for ASIP. It may not necessarily be applicable to this product.
NCBI Accession #
NP_996674.1
[Other Products]
NCBI GenBank Nucleotide #
NM_206843.2
[Other Products]
UniProt Primary Accession #
Q29414
[Other Products]
UniProt Secondary Accession #
Q3T0R3; Q53Z62[Other Products]
UniProt Related Accession #
Q29414[Other Products]
Molecular Weight
28.4 kDa
NCBI Official Full Name
agouti-signaling protein
NCBI Official Symbol
ASIP??[Similar Products]
NCBI Protein Information
agouti-signaling protein
UniProt Protein Name
Agouti-signaling protein
UniProt Synonym Protein Names
Agouti switch protein
Protein Family
Agouti-signaling protein
UniProt Gene Name
ASIP??[Similar Products]
UniProt Synonym Gene Names
ASP??[Similar Products]
UniProt Comments for ASIP
Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) ().
Research Articles on ASIP
1. Our results provide evidence for a widespread expression of ASIP in bovine tissues at mRNA and, for the first time, at protein level.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
