Product Name
Anti-Thrombin III antibody (Serpinc1), ELISA Kit
Full Product Name
Mouse Anti-Thrombin III antibody ELISA Kit
Product Synonym Names
Mouse Anti-Thrombin III antibody ELISA Kit; Anti-Thrombin III antibody
Product Gene Name
Serpinc1 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for P32261
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of Serpinc1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Serpinc1 purchase
MBS9310362 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Anti-Thrombin III antibody (Serpinc1) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Serpinc1. The ELISA analytical biochemical technique of the MBS9310362 kit is based on Serpinc1 antibody-Serpinc1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Serpinc1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Serpinc1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for Serpinc1. It may not necessarily be applicable to this product.
NCBI Accession #
AAB23965.1
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UniProt Primary Accession #
P32261
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UniProt Related Accession #
P32261[Other Products]
Molecular Weight
52,004 Da[Similar Products]
NCBI Official Full Name
antithrombin III
NCBI Official Synonym Full Names
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
NCBI Official Symbol
Serpinc1??[Similar Products]
NCBI Official Synonym Symbols
At3; At-3; ATIII; AI114908
??[Similar Products]
NCBI Protein Information
antithrombin-III; serpin C1; anti-thrombin 3; serpin peptidase inhibitor, clade C, member 1; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
UniProt Protein Name
Antithrombin-III
UniProt Synonym Protein Names
Serpin C1
Protein Family
Antithrombin
UniProt Gene Name
Serpinc1??[Similar Products]
UniProt Synonym Gene Names
At3; ATIII??[Similar Products]
UniProt Entry Name
ANT3_MOUSE
UniProt Comments for Serpinc1
SERPINC1: Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin. Defects in SERPINC1 are the cause of antithrombin III deficiency (AT3D). AT3D is an important risk factor for hereditary thrombophilia, a hemostatic disorder characterized by a tendency to recurrent thrombosis. AT3D is classified into 4 types. Type I: characterized by a 50% decrease in antigenic and functional levels. Type II: has defects affecting the thrombin- binding domain. Type III: alteration of the heparin-binding domain. Plasma AT-III antigen levels are normal in type II and III. Type IV: consists of miscellaneous group of unclassifiable mutations. Belongs to the serpin family.
Protein type: Inhibitor; Secreted, signal peptide; Secreted
Cellular Component: extracellular space; extracellular region
Molecular Function: heparin binding; serine-type endopeptidase inhibitor activity; protease binding; protease inhibitor activity
Biological Process: hemostasis; negative regulation of inflammatory response; negative regulation of peptidase activity; blood coagulation; response to nutrient
Research Articles on Serpinc1
1. RNA interference of Serpinc1 and/or Proc allows for evaluation of the function of these genes in vivo and provides a novel, controlled mouse model for spontaneous venous thrombosis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
