Product Name
Ap4s1, Blocking Peptide
Full Product Name
Ap4s1 Peptide - N-terminal region
Product Gene Name
Ap4s1 blocking peptide
[Similar Products]
Product Synonym Gene Name
AI314282[Similar Products]
Ap4s1 peptide (MBS3235660) is used for blocking the activity of Ap4s1 antibody (MBS3210705)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
KFFLMVNKQG QTRLSKYYEH VDINKRALLE TEVSKSCLSR SSEQCSFIEY
3D Structure
ModBase 3D Structure for Q9WVL1
Species Reactivity
Mouse, Human
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of Ap4s1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Ap4s1 blocking peptide
This is a synthetic peptide designed for use in combination with anti-Ap4s1 Antibody, made
Target Description: Ap4s1 is a subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
Product Categories/Family for Ap4s1 blocking peptide
Peptide
Applications Tested/Suitable for Ap4s1 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for Ap4s1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_068356
[Other Products]
NCBI GenBank Nucleotide #
NM_021710
[Other Products]
UniProt Primary Accession #
Q9WVL1
[Other Products]
UniProt Related Accession #
Q9WVL1[Other Products]
NCBI Official Full Name
AP-4 complex subunit sigma-1 isoform 2
NCBI Official Synonym Full Names
adaptor-related protein complex AP-4, sigma 1
NCBI Official Symbol
Ap4s1??[Similar Products]
NCBI Official Synonym Symbols
AI314282
??[Similar Products]
NCBI Protein Information
AP-4 complex subunit sigma-1
UniProt Protein Name
AP-4 complex subunit sigma-1
UniProt Synonym Protein Names
AP-4 adaptor complex subunit sigma-1; Adaptor-related protein complex 4 subunit sigma-1;
Sigma-1 subunit of AP-4; Sigma-4-adaptin; Sigma4-adaptin
Protein Family
AP-4 complex
UniProt Gene Name
Ap4s1??[Similar Products]
UniProt Synonym Gene Names
Sigma4-adaptin??[Similar Products]
UniProt Entry Name
AP4S1_MOUSE
NCBI Summary for Ap4s1
This gene encodes the sigma subunit of the adaptor-related protein complex 4 which mediates intracellular membrane trafficking along the endocytic and secretory transport pathways. This complex contains four subunits, beta, epsilon, mu, and sigma, and belongs to a family of five adapter protein complexes, including three clathrin-associated complexes and two non clathrin-associated complexes, that localize to different intracellular compartments and mediate membrane vesicle trafficking using distinct pathways. In humans, loss-of-function mutations in this gene have been linked to specific adapter complex 4 deficiency disorders including hereditary spastic paraplegia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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