Product Name
AP-4 complex subunit sigma-1 (AP4S1), Recombinant Protein
Full Product Name
Recombinant Bovine AP-4 complex subunit sigma-1 (AP4S1)
Product Gene Name
AP4S1 recombinant protein
[Similar Products]
Product Synonym Gene Name
AP4S1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-144aa, full length protein
Sequence
MIKFFLMVNK QGQTRLSKYY EHVEINKRTL LETEVIKSCL SRSNEQCSFI EYKDFKLIYR QYAALFIVVG VNDTENEMAI YEFIHNFVEV LDDYFSRVSE LDIMFNLDKV HIILDEMVLN GCIVETNRAR ILAPLLILDK MSDS
3D Structure
ModBase 3D Structure for Q3ZBB6
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of AP4S1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AP4S1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001035693.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001040603.2
[Other Products]
UniProt Primary Accession #
Q3ZBB6
[Other Products]
UniProt Related Accession #
Q3ZBB6[Other Products]
Molecular Weight
16,991 Da
NCBI Official Full Name
AP-4 complex subunit sigma-1
NCBI Official Synonym Full Names
adaptor related protein complex 4 sigma 1 subunit
NCBI Official Symbol
AP4S1??[Similar Products]
NCBI Protein Information
AP-4 complex subunit sigma-1
UniProt Protein Name
AP-4 complex subunit sigma-1
UniProt Synonym Protein Names
AP-4 adaptor complex subunit sigma-1; Adaptor-related protein complex 4 subunit sigma-1;
Sigma-1 subunit of AP-4; Sigma-4-adaptin; Sigma4-adaptin
Protein Family
AP-4 complex
UniProt Gene Name
AP4S1??[Similar Products]
UniProt Synonym Gene Names
Sigma4-adaptin??[Similar Products]
UniProt Comments for AP4S1
Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
