Full Product Name
ACBD5 antibody - N-terminal region
Product Gene Name
anti-ACBD5 antibody
[Similar Products]
Product Synonym Gene Name
DKFZp434A2417; KIAA1996[Similar Products]
Antibody/Peptide Pairs
ACBD5 peptide (MBS3232565) is used for blocking the activity of ACBD5 antibody (MBS3207600)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: ADTRSVHETR FEAAVKVIQS LPKNGSFQPT NEMMLKFYSF YKQATEGPCK
3D Structure
ModBase 3D Structure for Q5T8D3
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ACBD5
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ACBD5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACBD5 antibody
This is a rabbit polyclonal antibody against ACBD5. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: ACBD5 contains 1 ACB (acyl-CoA-binding) domain. The function of the ACBD5 protein is not known.
Product Categories/Family for anti-ACBD5 antibody
Polyclonal; Membrane Protein; DNA/RNA/Protein Interactions;
Applications Tested/Suitable for anti-ACBD5 antibody
Western Blot (WB)
Western Blot (WB) of anti-ACBD5 antibody
WB Suggested Anti-ACBD5 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human brain
NCBI/Uniprot data below describe general gene information for ACBD5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001035938
[Other Products]
NCBI GenBank Nucleotide #
NM_001042473
[Other Products]
UniProt Primary Accession #
Q5T8D3
[Other Products]
UniProt Related Accession #
Q5T8D3[Other Products]
NCBI Official Full Name
acyl-CoA-binding domain-containing protein 5 isoform 2
NCBI Official Synonym Full Names
acyl-CoA binding domain containing 5
NCBI Official Symbol
ACBD5??[Similar Products]
NCBI Protein Information
acyl-CoA-binding domain-containing protein 5
UniProt Protein Name
Acyl-CoA-binding domain-containing protein 5
Protein Family
Acyl-CoA-binding domain-containing protein
UniProt Gene Name
ACBD5??[Similar Products]
UniProt Synonym Gene Names
KIAA1996??[Similar Products]
NCBI Summary for ACBD5
This gene encodes a member of the acyl-Coenzyme A binding protein family, known to function in the transport and distribution of long chain acyl-Coenzyme A in cells. This gene may play a role in the differentiation of megakaryocytes and formation of platelets. A related protein in yeast is involved in autophagy of peroxisomes. A mutation in this gene has been associated with autosomal dominant thrombocytopenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
UniProt Comments for ACBD5
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
Research Articles on ACBD5
1. ACBD5 captures VLC-CoAs on the cytosolic side of the peroxisomal membrane so that the transport of VLC-CoAs into peroxisomes and subsequent beta-oxidation thereof can proceed efficiently.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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