Product Name
Dynein intermediate chain 1, axonemal (Dnai1), Recombinant Protein
Full Product Name
Recombinant Rat Dynein intermediate chain 1, axonemal (Dnai1)
Product Gene Name
Dnai1 recombinant protein
[Similar Products]
Product Synonym Gene Name
Dnai1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-705aa, full length protein
Sequence
MPSKQIRKQS VILTRGARKR EEDSGTDVGE GADDWAQSKA AVRPPDQLEL TDAELKEEFT RILTANNPHA PQNIVRYSFK ERTYKLIGFV NQMAIHFSQV GNLIPKDSDE GRRQHYRDEL VAGSQESVKV VTSDTEILEE EEEPKEGEGE GEGEAEGEAE AGSQTDVPAA AETTEKVIEE ELMAPVQPKE RKLTNQFNFS ERASQTFNNP LRDRECQMEP PPRTNFSATA NQWEIYDAYV DELEKLEKTK EKEKTKTPVA KKTEKMAMRK LTSMESQSDD ITKVTQAAKI VERMVNQNTY DDVAQDFKYY EDAADEYRDQ EGTLLPLWKF QNDKAKRLAV TALCWNPKYK DLFAVGHGSY DFMKQSRGML LLYSMKNPSF PEYMFSSESG IMCLDMHMDH PYLVVVGYYD GNVAIYNLKK PHSQPCFRST SKSGKHTDPV WQVKWQKDDM DHNLNFFSVS SDGRIVSWTL VKSELVHIDV IKLKDEGSTT EIPEGLQLHT VGCGTAFDFH KEIDYLFLVG TEEGKIYKCS KSYSSQFLDT YDAHNMAVDA VLWNPYHARV FISCSSDWTV KIWDHAIKTP MFIYDLNAAV GDVAWAPYSS TVFAAVTTDG KAHVFDLAVN KYEAICNQPV VAKKKNKITH VQFNPIHPII IVGDDRGHIT CLKLSPNLRK MPKEKKGQEV QKGPAVEIAK LDKLLNLVRE VKTKT
3D Structure
ModBase 3D Structure for Q5XIL8
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Dnai1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Dnai1 recombinant protein
The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome.
NCBI/Uniprot data below describe general gene information for Dnai1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001019513.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001024342.1
[Other Products]
UniProt Primary Accession #
Q5XIL8
[Other Products]
UniProt Related Accession #
Q5XIL8[Other Products]
Molecular Weight
80,073 Da
NCBI Official Full Name
dynein intermediate chain 1, axonemal
NCBI Official Synonym Full Names
dynein, axonemal, intermediate chain 1
NCBI Official Symbol
Dnai1??[Similar Products]
NCBI Official Synonym Symbols
Dnaic1
??[Similar Products]
NCBI Protein Information
dynein intermediate chain 1, axonemal
UniProt Protein Name
Dynein intermediate chain 1, axonemal
UniProt Synonym Protein Names
Axonemal dynein intermediate chain 1
UniProt Gene Name
Dnai1??[Similar Products]
UniProt Comments for Dnai1
Part of the dynein complex of respiratory cilia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
