Product Name
Olfactory guanylyl cyclase GC-D (Gucy2d), Recombinant Protein
Full Product Name
Recombinant Rat Olfactory guanylyl cyclase GC-D (Gucy2d), partial
Product Gene Name
Gucy2d recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
67-475
Sequence
RETF TLGVLGPWDC DPIFAQALPS MATQLAVDRV NQDASLLLGS QLDFKILPTG CDTPHALATF VAHRNTVAAF IGPVNPGYCP AAALLAQGWG KSLFSWACGA PEGGGALVPT LPSMADVLLS VMRHFGWARL AIVSSHQDIW VTTAQQLATA FRAHGLPIGL ITSLGPGEKG ATEVCKQLHS VHGLKIVVLC MHSALLGGLE QTVLLRCARE EGLTDGRLVF LPYDTLLFAL PYRNRSYLVL DDDGPLQEAY DAVLTISLDT SPESHAFTAT KMRGGAAANL GPEQVSPLFG TIYDAVILLA HALNHSETHG TGLSGAHLGN HIRALDVAGF SQRIRIDGKG RRLPQYVILD TNGEGSQLVP THILDVSTQQ VQPLGTAVHF PGGSPPAHDA SCWFDPNTLC IRGVQ
3D Structure
ModBase 3D Structure for P51839
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Gucy2d recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Gucy2d recombinant protein
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
NCBI/Uniprot data below describe general gene information for Gucy2d. It may not necessarily be applicable to this product.
NCBI Accession #
NP_570093.1
[Other Products]
NCBI GenBank Nucleotide #
NM_130737.4
[Other Products]
UniProt Primary Accession #
P51839
[Other Products]
UniProt Related Accession #
P51839[Other Products]
Molecular Weight
121,975 Da
NCBI Official Full Name
olfactory guanylyl cyclase GC-D
NCBI Official Synonym Full Names
guanylate cyclase 2d
NCBI Official Symbol
Gucy2d??[Similar Products]
NCBI Protein Information
olfactory guanylyl cyclase GC-D
UniProt Protein Name
Olfactory guanylyl cyclase GC-D
UniProt Synonym Protein Names
Guanylate cyclase, olfactory
Protein Family
Olfactory guanylyl cyclase
UniProt Gene Name
Gucy2d??[Similar Products]
NCBI Summary for Gucy2d
member of the membrane receptor guanyly cyclase family, specifically expressed in a subpopulation of olfactory sensory neurons; may function directly in odor recognition [RGD, Feb 2006]
UniProt Comments for Gucy2d
May function directly in odor recognition or in modulating the sensitivity of a subpopulation of sensory neurons to specific odors.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
