Product Name
ATP6V1C2, cDNA Clone
Full Product Name
ATP6V1C2 cDNA Clone
Product Gene Name
ATP6V1C2 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgtcggagt tttggttaat ttctgcccct ggcgataagg aaaatttgca agctctggag aggatgaata ctgtaacctc caagtccaac ctgtcttata ataccaaatt cgctattcct gacttcaagg tggggacctt ggattccctg gttggcctct ctgatgagtt ggggaaactc gacacctttg ctgaaagcct cataaggaga atggctcaga gcgtggtgga agtcatggag gactcaaagg ggaaggtcca ggagcacctc ctggcaaacg gagttgactt aacatccttt gtgacccact ttgaatggga catggccaaa tatcctgtca agcagccgct cgtgagtgtg gtggacacaa tagccaagca actggcgcag atcgagatgg acctgaagtc ccgaacggcc gcctacgaca ctctgaagac aaacctggag aacctggaaa agaaatccat ggggaacctc ttcacccgga cactgagtga tattgtgagc aaagaggact tcgtgctgga ttctgaatat ctcgtcacac ttctggtcat cgtccccaaa ccaaactact cacaatggca aaaaacctac gaatctctct cagacatggt ggtccctcga tcaaccaaac tcattactga ggacaaggaa gggggccttt tcactgtgac tctgtttcga aaagtgattg aagatttcaa aaccaaggcc aaagaaaaca agttcactgt tcgtgaattt tactatgatg agaaggaaat tgaaagggaa agggaggaga tggccagatt gctgtctgat aagaagcaac agtatggccc cctgctgcgc tggctcaagg tgaacttcag tgaagccttc attgcctgga tccacatcaa ggccctgaga gtgtttgtgg agtccgtgct caggtatgga ctaccagtga acttccaggc agtgctcctg cagccgcata agaagtcatc caccaagcgt ttaagagagg ttctaaactc tgtcttccga catctggatg aagtagccgc tacaagtata ctggatgcat ctgtggagat cccgggactg caactcaata accaagacta ttttccttat gtctacttcc atattgacct tagtcttctt gactag
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ATP6V1C2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ATP6V1C2. It may not necessarily be applicable to this product.
NCBI Accession #
BC012142
[Other Products]
UniProt Secondary Accession #
Q96EL8[Other Products]
UniProt Related Accession #
Q8NEY4[Other Products]
Molecular Weight
43,865 Da
NCBI Official Full Name
Homo sapiens ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2, mRNA
NCBI Official Synonym Full Names
ATPase H+ transporting V1 subunit C2
NCBI Official Symbol
ATP6V1C2??[Similar Products]
NCBI Official Synonym Symbols
VMA5; ATP6C2
??[Similar Products]
NCBI Protein Information
V-type proton ATPase subunit C 2
UniProt Protein Name
V-type proton ATPase subunit C 2
UniProt Synonym Protein Names
Vacuolar proton pump subunit C 2
Protein Family
V-type proton ATPase
UniProt Gene Name
ATP6V1C2??[Similar Products]
UniProt Synonym Gene Names
V-ATPase subunit C 2??[Similar Products]
UniProt Entry Name
VATC2_HUMAN
NCBI Summary for ATP6V1C2
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for ATP6V1C2
ATP6V1C2: Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase C subunit family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.3.14; Hydrolase; Energy Metabolism - oxidative phosphorylation
Chromosomal Location of Human Ortholog: -
Cellular Component: cytosol; lysosomal membrane
Molecular Function: protein dimerization activity
Biological Process: insulin receptor signaling pathway; positive regulation of Wnt receptor signaling pathway; transferrin transport
Research Articles on ATP6V1C2
1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Precautions
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Disclaimer
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