Product Name
ARMS2, Polyclonal Antibody
Popular Item
Full Product Name
ARMS2 Polyclonal Antibody
Product Gene Name
anti-ARMS2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P0C7Q2
Purity/Purification
Affinity purification
Immunogen
Recombinant protein of human ARMS2
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-ARMS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-ARMS2 antibody
Polyclonal
Applications Tested/Suitable for anti-ARMS2 antibody
Western Blot (WB)
Application Notes for anti-ARMS2 antibody
WB: 1:200 - 1:1000
Western Blot (WB) of anti-ARMS2 antibody
Western blot analysis of extracts of mouse eye, using ARMS2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
NCBI/Uniprot data below describe general gene information for ARMS2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001093137.1
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NCBI GenBank Nucleotide #
NM_001099667.1
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UniProt Primary Accession #
P0C7Q2
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UniProt Secondary Accession #
B2Y7I5[Other Products]
UniProt Related Accession #
P0C7Q2[Other Products]
Molecular Weight
Calculated MW: 11kDa
Molecular Weight: 107
NCBI Official Full Name
age-related maculopathy susceptibility protein 2
NCBI Official Synonym Full Names
age-related maculopathy susceptibility 2
NCBI Official Symbol
ARMS2??[Similar Products]
NCBI Official Synonym Symbols
ARMD8
??[Similar Products]
NCBI Protein Information
age-related maculopathy susceptibility protein 2
UniProt Protein Name
Age-related maculopathy susceptibility protein 2
Protein Family
Age-related maculopathy susceptibility protein
UniProt Gene Name
ARMS2??[Similar Products]
UniProt Entry Name
ARMS2_HUMAN
NCBI Summary for ARMS2
This gene encodes a protein that is thought to play a role in diseases in the elderly. Mutations in this gene have been associated with age-related macular degeneration. [provided by RefSeq, Oct 2008]
UniProt Comments for ARMS2
ARMS2: Defects in ARMS2 influence susceptibility to age-related macular degeneration type 8 (ARMD8). ARMD is the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid (known as drusen) that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch's membrane. ARMD is likely to be a mechanistically heterogeneous group of disorders, and the specific disease mechanisms that underlie the vast majority of cases are currently unknown. However, a number of studies have suggested that both genetic and environmental factors are likely to play a role.
Chromosomal Location of Human Ortholog: 10q26.13
Cellular Component: mitochondrion; photoreceptor inner segment
Biological Process: retinal homeostasis
Disease: Macular Degeneration, Age-related, 8
Research Articles on ARMS2
1. No significant interaction was found between DHA supplementation benefit and ARMS2 A69S SNP.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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