Product Name
Antithrombin (AT), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to Antithrombin (AT)
Product Gene Name
anti-AT antibody
[Similar Products]
Matching Pairs
Unconjugated Antibody: Antithrombin (MBS2028564)
Immunogen: Antithrombin (MBS2029809)
Matching Pairs
Unconjugated Antibody: Antithrombin (MBS2028564)
APC-CY7 Conjugated Antibody: Antithrombin (AT) (MBS2064817)
Matching Pairs
Unconjugated Antibody: Antithrombin (MBS2028564)
PE Conjugated Antibody: Antithrombin (AT) (MBS2064818)
Matching Pairs
Unconjugated Antibody: Antithrombin (MBS2028564)
APC Conjugated Antibody: Antithrombin (AT) (MBS2064819)
Matching Pairs
Unconjugated Antibody: Antithrombin (MBS2028564)
Cy3 Conjugated Antibody: Antithrombin (AT) (MBS2064820)
Matching Pairs
Unconjugated Antibody: Antithrombin (MBS2028564)
FITC Conjugated Antibody: Antithrombin (AT) (MBS2064821)
Matching Pairs
Unconjugated Antibody: Antithrombin (MBS2028564)
HRP Conjugated Antibody: Antithrombin (AT) (MBS2064822)
Matching Pairs
Unconjugated Antibody: Antithrombin (MBS2028564)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
Matching Pairs
Unconjugated Antibody: Antithrombin (MBS2028564)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
Matching Pairs
Unconjugated Antibody: Antithrombin (MBS2028564)
Biotin Conjugated Antibody: Antithrombin (AT) (MBS2094395)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P41361
Species Reactivity
Bovine
Specificity
The antibody is a rabbit polyclonal antibody raised against AT. It has beenselected for its ability to recognize AT in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Concentration
200ug/ml (lot specific)
Fragment
AT (His33~Asp465)
Organism Species
Bos taurus; Bovine (Cattle)
Immunogen
Recombinant AT (His33~Asp465) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2064819
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Other Notes
Small volumes of anti-AT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-AT antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes for anti-AT antibody
Western blotting: 0.2-2ug/mL;1:250-2500
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Western Blot (WB) of anti-AT antibody
Western Blot: Sample: Bovine Serum; Primary Ab: 1ug/ml Rabbit Anti-Bovine AT Antibody Second Ab: 0.2ug/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Western Blot (WB) of anti-AT antibody
Western Blot: Sample: Recombinant protein.

NCBI/Uniprot data below describe general gene information for AT. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001029870.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001034698.2
[Other Products]
UniProt Primary Accession #
P41361
[Other Products]
UniProt Secondary Accession #
Q3SZQ7[Other Products]
UniProt Related Accession #
P41361[Other Products]
Molecular Weight
52,347 Da
NCBI Official Full Name
antithrombin-III
NCBI Official Synonym Full Names
serpin family C member 1
NCBI Official Symbol
SERPINC1??[Similar Products]
NCBI Official Synonym Symbols
AT3
??[Similar Products]
NCBI Protein Information
antithrombin-III
UniProt Protein Name
Antithrombin-III
UniProt Synonym Protein Names
Serpin C1
Protein Family
Antithrombin
UniProt Gene Name
SERPINC1??[Similar Products]
UniProt Synonym Gene Names
AT3; ATIII??[Similar Products]
UniProt Comments for AT
Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin ().
Research Articles on AT
1. ATIII may be protective in HIV-1 disease by inhibiting HIV-1 replication
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.