Product Name
ATAD3B/ATPase Family AAA Domain-Containing Protein 3B, ELISA Kit
Full Product Name
Human ATAD3B/ATPase Family AAA Domain-Containing Protein 3B ELISA Kit
Product Synonym Names
ATPase family AAA domain-containing protein 3B; AAA-TOB3; KIAA1273; TOB3
Product Gene Name
ATAD3B elisa kit
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q5T9A4
Specificity
Natural and recombinant Human ATPase family AAA domain-containing protein 3B
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of ATAD3B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for ATAD3B purchase
MBS2890937 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ATAD3B/ATPase Family AAA Domain-Containing Protein 3B, ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ATAD3B. The ELISA analytical biochemical technique of the MBS2890937 kit is based on ATAD3B antibody-ATAD3B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ATAD3B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ATAD3B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for ATAD3B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_114127
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NCBI GenBank Nucleotide #
NM_031921.5
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UniProt Primary Accession #
Q5T9A4
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UniProt Related Accession #
Q5T9A4[Other Products]
NCBI Official Full Name
ATPase family AAA domain-containing protein 3B isoform AAA-TOB3l
NCBI Official Synonym Full Names
ATPase family AAA domain containing 3B
NCBI Official Symbol
ATAD3B??[Similar Products]
NCBI Official Synonym Symbols
TOB3; AAA-TOB3
??[Similar Products]
NCBI Protein Information
ATPase family AAA domain-containing protein 3B
UniProt Protein Name
ATPase family AAA domain-containing protein 3B
UniProt Synonym Protein Names
AAA-TOB3
Protein Family
ATPase family AAA domain-containing protein
UniProt Gene Name
ATAD3B??[Similar Products]
UniProt Synonym Gene Names
KIAA1273; TOB3??[Similar Products]
UniProt Entry Name
ATD3B_HUMAN
NCBI Summary for ATAD3B
The protein encoded by this gene is localized to the mitochondrial inner membrane, where it can bind to a highly-related protein, ATAD3A. ATAD3A appears to interact with matrix nucleoid complexes, and the encoded protein negatively regulates that interaction. This gene is expressed almost exclusively in pluripotent embryonic stem cells and some cancer cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
UniProt Comments for ATAD3B
ATAD3B: May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes. Belongs to the AAA ATPase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: mitochondrial inner membrane
Molecular Function: ATP binding
Research Articles on ATAD3B
1. AAA-TOB3 was highly expressed in lung adenocarcinoma, and the up-regulation of AAA-TOB3 correlated with lymph node metastasis and advanced stage of lung adenocarcinoma.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
