Product Name
ATAD3B, Polyclonal Antibody
Full Product Name
ATAD3B Antibody
Product Synonym Names
AAA-TOB3; KIAA1273; TOB3
Product Gene Name
anti-ATAD3B antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of ATAD3B
Calculated Molecular Weight: 72kd
Buffer
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-104095
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-ATAD3B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ATAD3B antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for ATAD3B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_114127.3
[Other Products]
NCBI GenBank Nucleotide #
NM_031921.4
[Other Products]
UniProt Secondary Accession #
Q6ZRB5; Q9BUK4; Q9ULE7; A8K3H1[Other Products]
UniProt Related Accession #
Q5T9A4[Other Products]
Molecular Weight
67,608 Da
NCBI Official Full Name
ATPase family AAA domain-containing protein 3B
NCBI Official Synonym Full Names
ATPase family, AAA domain containing 3B
NCBI Official Symbol
ATAD3B??[Similar Products]
NCBI Official Synonym Symbols
TOB3; AAA-TOB3
??[Similar Products]
NCBI Protein Information
ATPase family AAA domain-containing protein 3B; AAA-ATPase TOB3
UniProt Protein Name
ATPase family AAA domain-containing protein 3B
UniProt Synonym Protein Names
AAA-TOB3
Protein Family
ATPase family AAA domain-containing protein
UniProt Gene Name
ATAD3B??[Similar Products]
UniProt Synonym Gene Names
KIAA1273; TOB3??[Similar Products]
UniProt Entry Name
ATD3B_HUMAN
NCBI Summary for ATAD3B
ATAD3A (MIM 612316) and ATAD3B are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008]
UniProt Comments for ATAD3B
ATAD3B: May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes. Belongs to the AAA ATPase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: mitochondrial inner membrane
Molecular Function: ATP binding
Research Articles on ATAD3B
1. exploring ATAD3 mRNA expression, we confirmed the existence of an alternative splicing in rodent and of several mRNA isoforms in human
Precautions
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Disclaimer
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