Product Name
ACTL7A, cDNA Clone
Full Product Name
ACTL7A cDNA Clone
Product Gene Name
ACTL7A cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgtgggctc caccagcagc aatcatgggg gatgggccca ccaagaaggt gggcaaccag gcccccctgc agacacaggc cctccagact gcctctttaa gggatggccc ggcgaagcgg gccgtgtggg tccgccatac gagttcagag ccacaagaac ctactgaatc aaaggcagcc aaggagaggc ccaagcagga ggtgaccaaa gcagtggtcg tggacctggg cactggctac tgtaaatgtg gctttgccgg cctgccaaga cccacccaca agatctcaac aacggtgggc aagccctaca tggagaccgc caagactggg gataatcgca aggagacatt cgtggggcag gaactcaaca acacaaacgt tcatctcaag ctggttaacc ctctgcgaca tggcatcatc gtggactggg atacagtgca ggatatctgg gaatatctct tccgacaaga gatgaagatc gccccggagg agcatgcggt cttggtttca gacccgccac tgagcccaca caccaacaga gagaaatatg ctgaaatgct gtttgaagcc ttcaacaccc ctgcaatgca catcgcctac cagtcgcgcc tgtccatgta ctcctatgga aggacctccg gcctggtggt ggaggtgggc catggcgtgt cctacgtggt ccccatctac gagggttatc ctttgcccag catcaccgga aggctggact acgcgggctc tgacctgaca gcctacctgc tgggcctgct gaacagtgcg gggaacgaat tcacccagga ccagatgggc atcgtggagg acatcaagaa gaaatgctgc tttgtggccc tggatcccat tgaggagaag aaagtccctc tcagtgagca tacgatccgc tacgtgctgc cggatgggaa ggagattcag ctgtgccagg aacggttcct ctgctcggag atgttcttca agccatctct catcaagtcc atgcagctgg gcctccacac ccaaaccgtg tcctgcctta acaagtgtga catcgccctc aaacgggacc tcatggggaa catcctgctc tgcgggggca gcacgatgct cagtggcttc cctaaccgtc tgcagaagga gctaagcagc atgtgtccca atgacacccc gcaggtaaac gtgctgcctg aaagagacag tgccgtgtgg accggtggct ccatcctggc ctcacttcag ggtttccaac cattatgggt ccaccgcttt gagtacgagg aacacgggcc tttcttcctc tacagaaggt gcttctga
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ACTL7A cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ACTL7A. It may not necessarily be applicable to this product.
NCBI Accession #
BC014610
[Other Products]
UniProt Secondary Accession #
Q5JSV0; B2RC83[Other Products]
UniProt Related Accession #
Q9Y615[Other Products]
Molecular Weight
48,644 Da
NCBI Official Full Name
Homo sapiens actin-like 7A, mRNA
NCBI Official Synonym Full Names
actin like 7A
NCBI Official Symbol
ACTL7A??[Similar Products]
NCBI Protein Information
actin-like protein 7A
UniProt Protein Name
Actin-like protein 7A
UniProt Synonym Protein Names
Actin-like-7-alpha
Protein Family
Actin-like protein
UniProt Gene Name
ACTL7A??[Similar Products]
UniProt Entry Name
ACL7A_HUMAN
NCBI Summary for ACTL7A
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of ***** tissues, however, its exact function is not known. [provided by RefSeq, Jul 2008]
UniProt Comments for ACTL7A
AL7A: an actin-related protein (ARP). Shares significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. Its gene (ACTL7A), and a related gene, ACTL7B, are intronless. Expressed in a wide variety of ***** tissues, however, its exact function is not known.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 9q31
Cellular Component: cytoplasm; Golgi apparatus; nucleus; protein complex
Molecular Function: protein binding; structural constituent of cytoskeleton
Research Articles on ACTL7A
1. Anti-ACTL7a antibodies may cause infertility in mice because the in vitro treatment of mouse spermatozoa with ACTL7a antibody-containing serum markedly reduced the fertilizing potential of the spermatozoa.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
