Full Product Name
ACTG2 Antibody - C-terminal region
Product Gene Name
anti-ACTG2 antibody
[Similar Products]
Product Synonym Gene Name
ACT; ACTA3; ACTE; ACTL3; ACTSG[Similar Products]
Antibody/Peptide Pairs
ACTG2 peptide (MBS3241787) is used for blocking the activity of ACTG2 antibody (MBS3216888)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: TMKIKIIAPP ERKYSVWIGG SILASLSTFQ QMWISKPEYD EAGPSIVHRK
3D Structure
ModBase 3D Structure for P63267
Species Reactivity
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 93%; Zebrafish: 93%
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human ACTG2
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-ACTG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACTG2 antibody
This is a rabbit polyclonal antibody against ACTG2. It was validated on Western Blot
Target Description: Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.
Product Categories/Family for anti-ACTG2 antibody
Polyclonal; Various;
Applications Tested/Suitable for anti-ACTG2 antibody
Western Blot (WB)
Western Blot (WB) of anti-ACTG2 antibody
WB Suggested Anti-ACTG2 Antibody
Titration: 0.25 ug/ml
Positive Control: Fetal Lung
NCBI/Uniprot data below describe general gene information for ACTG2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001606
[Other Products]
NCBI GenBank Nucleotide #
NM_001615
[Other Products]
UniProt Primary Accession #
P63267
[Other Products]
UniProt Related Accession #
P63267[Other Products]
NCBI Official Full Name
actin, gamma-enteric smooth muscle isoform 1
NCBI Official Synonym Full Names
actin gamma 2, smooth muscle
NCBI Official Symbol
ACTG2??[Similar Products]
NCBI Official Synonym Symbols
ACT; ACTE; VSCM; ACTA3; ACTL3; ACTSG
??[Similar Products]
NCBI Protein Information
actin, gamma-enteric smooth muscle
UniProt Protein Name
Actin, gamma-enteric smooth muscle
UniProt Synonym Protein Names
Alpha-actin-3; Gamma-2-actin; Smooth muscle gamma-actin
UniProt Gene Name
ACTG2??[Similar Products]
UniProt Synonym Gene Names
ACTA3; ACTL3; ACTSG??[Similar Products]
UniProt Entry Name
ACTH_HUMAN
NCBI Summary for ACTG2
Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010]
UniProt Comments for ACTG2
ACTG2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.
Protein type: Cytoskeletal; Contractile; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2p13.1
Cellular Component: extracellular space; cytoskeleton; cytosol
Molecular Function: ATP binding
Biological Process: muscle contraction
Disease: Visceral Myopathy
Research Articles on ACTG2
1. G; rs864309491) in exon 3">fetus with intestinal pseudo-obstruction heterozygous for p.R63G pathogenic variant (NM_001615.3 c.187C>G; rs864309491) in exon 3
Precautions
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Disclaimer
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