Full Product Name
Anti-ACTG2 Antibody (aa343-371) IHC-plus
Product Synonym Names
Rabbit Polyclonal to Human ACTG2; Human ACTG2; ACTA3; Actin-like protein; ACTSG; ACTE; Actin; alpha cardiac; ACTL3; Alpha-actin 3; Alpha-actin-3; Smooth muscle gamma-actin; Gamma-2-actin; Smooth muscle gamma actin
Product Gene Name
anti-ACTG2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P63267
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.09% sodium azide
Immunogen
ACTG2 antibody was raised against kLH-conjugated synthetic peptide from C-terminal region of human ACTG2.
Immunogen Description
KLH-conjugated synthetic peptide from C-terminal region of human ACTG2.
Immunogen Type
Synthetic peptide
Antigen Modification
aa343-371
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.
Other Notes
Small volumes of anti-ACTG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACTG2 antibody
ACTG2 Antibody, ACTA3 Antibody, Actin-like protein Antibody, ACTSG Antibody, ACTE Antibody, Actin, alpha cardiac Antibody, ACTL3 Antibody, Alpha-actin 3 Antibody, Alpha-actin-3 Antibody, Smooth muscle gamma-actin Antibody, Gamma-2-actin Antibody, Smooth muscle gamma actin Antibody Description: Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
Applications Tested/Suitable for anti-ACTG2 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-ACTG2 antibody
IHC-P (1:100)
WB (1:1000)
Immunohistochemistry (IHC) of anti-ACTG2 antibody
Anti-ACTG2 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

Western Blot (WB) of anti-ACTG2 antibody
ACTG2 Antibody western blot of CEM cell line lysates (35 ug/lane). The ACTG2 antibody detected the ACTG2 protein (arrow).

NCBI/Uniprot data below describe general gene information for ACTG2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001606.1
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NCBI GenBank Nucleotide #
NM_001615.3
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UniProt Primary Accession #
P63267
[Other Products]
UniProt Secondary Accession #
P12718; Q504R1; Q6FI22; B2R7E7; B4E315; D6W5H8; E9PG30[Other Products]
UniProt Related Accession #
P63267[Other Products]
Molecular Weight
37,083 Da
NCBI Official Full Name
actin, gamma-enteric smooth muscle isoform 1
NCBI Official Synonym Full Names
actin, gamma 2, smooth muscle, enteric
NCBI Official Symbol
ACTG2??[Similar Products]
NCBI Official Synonym Symbols
ACT; ACTE; VSCM; ACTA3; ACTL3; ACTSG
??[Similar Products]
NCBI Protein Information
actin, gamma-enteric smooth muscle
UniProt Protein Name
Actin, gamma-enteric smooth muscle
UniProt Synonym Protein Names
Alpha-actin-3; Gamma-2-actin; Smooth muscle gamma-actin
UniProt Gene Name
ACTG2??[Similar Products]
UniProt Synonym Gene Names
ACTA3; ACTL3; ACTSG??[Similar Products]
UniProt Entry Name
ACTH_HUMAN
NCBI Summary for ACTG2
Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010]
UniProt Comments for ACTG2
ACTG2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis; Contractile
Chromosomal Location of Human Ortholog: 2p13.1
Cellular Component: cytoplasm; cytosol; extracellular space; filopodium; lamellipodium
Molecular Function: ATP binding
Biological Process: muscle contraction
Disease: Visceral Myopathy
Research Articles on ACTG2
1. ACTG2 encodes g2 enteric actin and is the first gene to be clearly associated with Megacystis-microcolon-intestinal hypoperistalsis syndrome, suggesting an important role for contractile proteins in enteric smooth muscle disease.
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