Product Name
ACTG2, Polyclonal Antibody
Popular Item
Full Product Name
ACTG2 Antibody
Product Synonym Names
Actin; gamma-enteric smooth muscle; Alpha-actin-3; Gamma-2-actin; Smooth muscle gamma-actin; ACTG2; ACTA3; ACTL3; ACTSG
Product Gene Name
anti-ACTG2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS7002925 Technical Datasheet
Technical Datasheet PDF
3D Structure
ModBase 3D Structure for P63267
Purity/Purification
>95%,Protein G purified
Immunogen
Recombinant human Actin, gamma-enteric smooth muscle protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ACTG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACTG2 antibody
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Applications Tested/Suitable for anti-ACTG2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Western Blot (WB) of anti-ACTG2 antibody
Western blot
All lanes: ACTG2 antibody at 3ug/ml+CEM whole cell lysate
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 42,38 kDa
Observed band size: 42 kDa

Immunohistochemistry (IHC) of anti-ACTG2 antibody
Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7002925 at dilution of 1:100

Immunohistochemistry (IHC) of anti-ACTG2 antibody
Immunohistochemistry of paraffin-embedded human rectum tissue using MBS7002925 at dilution of 1:100

NCBI/Uniprot data below describe general gene information for ACTG2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001186822.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001199893.1
[Other Products]
UniProt Primary Accession #
P63267
[Other Products]
UniProt Secondary Accession #
P12718; Q504R1; Q6FI22; B2R7E7; B4E315; D6W5H8; E9PG30[Other Products]
UniProt Related Accession #
P63267[Other Products]
Molecular Weight
37,083 Da
NCBI Official Full Name
actin, gamma-enteric smooth muscle isoform 2
NCBI Official Synonym Full Names
actin, gamma 2, smooth muscle, enteric
NCBI Official Symbol
ACTG2??[Similar Products]
NCBI Official Synonym Symbols
ACT; ACTE; VSCM; ACTA3; ACTL3; ACTSG
??[Similar Products]
NCBI Protein Information
actin, gamma-enteric smooth muscle
UniProt Protein Name
Actin, gamma-enteric smooth muscle
UniProt Synonym Protein Names
Alpha-actin-3; Gamma-2-actin; Smooth muscle gamma-actin
UniProt Gene Name
ACTG2??[Similar Products]
UniProt Synonym Gene Names
ACTA3; ACTL3; ACTSG??[Similar Products]
UniProt Entry Name
ACTH_HUMAN
NCBI Summary for ACTG2
Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010]
UniProt Comments for ACTG2
ACTG2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.
Protein type: Contractile; Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 2p13.1
Cellular Component: cytoplasm; cytosol; extracellular space; filopodium; lamellipodium
Molecular Function: ATP binding
Biological Process: muscle contraction
Disease: Visceral Myopathy
Research Articles on ACTG2
1. ACTG2 encodes g2 enteric actin and is the first gene to be clearly associated with Megacystis-microcolon-intestinal hypoperistalsis syndrome, suggesting an important role for contractile proteins in enteric smooth muscle disease.
Precautions
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Disclaimer
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