For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

This item is specific for the beta subunit of human luteinizing hormone (LH) and cross reacts with the beta subunit of chorionic gonadotropin. Some reactivity has been observed with human TSH, FSH and prolactin.

Purified
Ig fraction - lyophilised

Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.

Small volumes of anti-LHB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS222680 is specific for the beta subunit of human luteinizing hormone (LH) and cross reacts with the beta subunit of chorionic gonadotropin. Some reactivity has been observed with human TSH, FSH and prolactin.

Immunohistology Frozen, Western Blot (WB)

Western Blotting: Minimum Dilution: 1/300; Maximum Dilution: 1/400

15,345 Da[Similar Products]

luteinizing hormone beta polypeptide

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Lutropin subunit beta

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LSHB_HUMAN

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]

LHB: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Defects in LHB are a cause of hypogonadism LHB-related (HGON-LHB). Hypogonadism is characterized by infertility and pseudohermaphroditism. Belongs to the glycoprotein hormones subunit beta family.

Protein type: Hormone; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: extracellular region

Molecular Function: hormone activity; receptor binding

Biological Process: progesterone biosynthetic process; cellular protein metabolic process; cell-cell signaling; male gonad development; peptide hormone processing; signal transduction

Disease: Fertile Eunuch Syndrome

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