Full Product Name
ETV7 Antibody, Biotin conjugated
Product Synonym Names
Transcription factor ETV7; ETS translocation variant 7; ETS-related protein Tel2; Tel-related Ets factor; Transcription factor Tel-2; ETV7; TEL2; TELB; TREF
Product Gene Name
anti-ETV7 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9Y603
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Transcription factor ETV7 protein (134-218AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ETV7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ETV7 antibody
Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity.
Applications Tested/Suitable for anti-ETV7 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for ETV7. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001193964.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001207035.1
[Other Products]
UniProt Primary Accession #
Q9Y603
[Other Products]
UniProt Secondary Accession #
Q5R3L3; Q5R3L4; Q9NZ65; Q9NZ66; Q9NZ68; Q9NZR8; Q9UNJ7; Q9Y5K4; B3KVC2; B4DVB6; B4E1G4[Other Products]
UniProt Related Accession #
Q9Y603[Other Products]
Molecular Weight
22,186 Da
NCBI Official Full Name
transcription factor ETV7 isoform 2
NCBI Official Synonym Full Names
ETS variant 7
NCBI Official Symbol
ETV7??[Similar Products]
NCBI Official Synonym Symbols
TEL2; TELB; TEL-2
??[Similar Products]
NCBI Protein Information
transcription factor ETV7
UniProt Protein Name
Transcription factor ETV7
UniProt Synonym Protein Names
ETS translocation variant 7; ETS-related protein Tel2; Tel-related Ets factor; Transcription factor Tel-2
Protein Family
Transcription factor
UniProt Gene Name
ETV7??[Similar Products]
UniProt Synonym Gene Names
TEL2; TELB; TREF??[Similar Products]
NCBI Summary for ETV7
The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).[provided by RefSeq, May 2011]
UniProt Comments for ETV7
ETV7: Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity. Belongs to the ETS family. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 6p21.31
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: cell differentiation; negative regulation of transcription from RNA polymerase II promoter; organ morphogenesis; transcription from RNA polymerase II promoter
Research Articles on ETV7
1. TEL2 plays a key role in nasopharyngeal carcinoma metastasis by directly down-regulating SERPINE1.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
