Product Name
ETV7, cDNA Clone
Full Product Name
ETV7 cDNA Clone
Product Gene Name
ETV7 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgcaggagg gagaattggc tatttctcct ataagccctg tggcagccat gcctccccta ggcacccacg tgcaagccag atgtgaagct caaattaacc tgctgggtga aggggggatc tgcaagctgc caggaagact ccgcatccag cccgcactgt ggagcaggga ggacgtgctg cactggctgc gctgggcaga gcaggagtac tctctgccat gcaccgcgga gcacgggttc gagatgaacg gacgcgccct ctgcatcctc accaaggacg acttccggca ccgtgcgccc agctcaggtg acgtcctgta tgagctgctc cagtacatca agacccagcg gcgagccctg gtgtgtggac ccttttttgg agggatcttc aggctgaaga cgcccaccca gcactctcca gtccccccgg aagaggtgac tggcccctct cagatggaca cccgaagggg ccacctgctg cagccaccag acccagggct taccagcaac ttcggccacc tggatgaccc tggcctggca aggtggaccc ctggcaagga ggagtccctc aacttatgtc actgtgcaga gctcggctgc aggacccagg gggtctgttc cttccccgcg atgccgcagg cccccattga cggcaggatc gctgactgcc gcctgctgtg ggattacgtg tatcagctgc tccttgatac ccgatatgag ccctacatca agtgggaaga caaggacgcc aagatcttcc gagttgtgga tccaaatggg ctcgccagac tctggggaaa tcacaagaac cgggtgaaca tgacctacga gaagatgtct cgtgccctgc gccactatta taagcttaat atcattaaga aggaaccggg gcagaaactc ctgttcagat ttctaaagac tccgggaaag atggtccagg acaagcacag ccacctggag ccgctggaga gccaggagca ggacagaata gagttcaagg acaagaggcc agaaatctct ccgtga
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ETV7 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ETV7. It may not necessarily be applicable to this product.
NCBI Accession #
BC035853
[Other Products]
UniProt Secondary Accession #
Q5R3L3; Q5R3L4; Q9NZ65; Q9NZ66; Q9NZ68; Q9NZR8; Q9UNJ7; Q9Y5K4; B3KVC2; B4DVB6; B4E1G4[Other Products]
UniProt Related Accession #
Q9Y603[Other Products]
Molecular Weight
22,186 Da
NCBI Official Full Name
Homo sapiens ets variant 7, mRNA
NCBI Official Synonym Full Names
ETS variant 7
NCBI Official Symbol
ETV7??[Similar Products]
NCBI Official Synonym Symbols
TEL2; TELB; TEL-2
??[Similar Products]
NCBI Protein Information
transcription factor ETV7
UniProt Protein Name
Transcription factor ETV7
UniProt Synonym Protein Names
ETS translocation variant 7; ETS-related protein Tel2; Tel-related Ets factor; Transcription factor Tel-2
Protein Family
Transcription factor
UniProt Gene Name
ETV7??[Similar Products]
UniProt Synonym Gene Names
TEL2; TELB; TREF??[Similar Products]
UniProt Entry Name
ETV7_HUMAN
NCBI Summary for ETV7
The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).[provided by RefSeq, May 2011]
UniProt Comments for ETV7
ETV7: Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity. Belongs to the ETS family. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 6p21
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: cell differentiation; negative regulation of transcription from RNA polymerase II promoter; organ morphogenesis; transcription from RNA polymerase II promoter
Research Articles on ETV7
1. TEL2 plays a key role in nasopharyngeal carcinoma metastasis by directly down-regulating SERPINE1.
Precautions
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Disclaimer
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