Human Transcription factor ETV7 (ETV7) ELISA kit; TEL-2; TEL2; TELB; Ets transcription factor TEL-2b; TEL2 oncogene; ets variant gene 7 (TEL2 oncogene) ; transcription factor ets; ets variant 7

For Research Use Only. Not for use in diagnostic procedures.

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

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Small volumes of ETV7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9323982 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ets variant 7 (ETV7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ETV7. The ELISA analytical biochemical technique of the MBS9323982 kit is based on ETV7 antibody-ETV7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ETV7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ETV7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ETV7 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

38,998 Da

ets variant 7

transcription factor ETV7; TEL2 oncogene; tel-related Ets factor; ETS-related protein Tel2; ETS translocation variant 7; Ets transcription factor TEL-2b; ets variant gene 7 (TEL2 oncogene)

Transcription factor ETV7

TEL2; TELB; TREF??[Similar Products]

ETV7_HUMAN

The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).[provided by RefSeq, May 2011]

ETV7: Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity. Belongs to the ETS family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 6p21

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; organ morphogenesis; negative regulation of transcription from RNA polymerase II promoter; cell differentiation

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