Product Name
CRB3, Blocking Peptide
Full Product Name
CRB3 Peptide - N-terminal region
Product Gene Name
CRB3 blocking peptide
[Similar Products]
CRB3 peptide (MBS3231585) is used for blocking the activity of CRB3 antibody (MBS3206621)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ANPGLGLLLA LGLPFLLARW GRAWGQIQTT SANENSTVLP SSTSSSSDGN
3D Structure
ModBase 3D Structure for Q9BUF7
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of CRB3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CRB3 blocking peptide
This is a synthetic peptide designed for use in combination with anti-CRB3 Antibody, made
Target Description: This gene encodes a member of the Crumbs family of proteins. This protein may play a role in epithelial cell polarity and is associated with tight junctions at the apical surface of epithelial cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Product Categories/Family for CRB3 blocking peptide
Peptide
NCBI/Uniprot data below describe general gene information for CRB3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_631900
[Other Products]
NCBI GenBank Nucleotide #
NM_139161
[Other Products]
UniProt Primary Accession #
Q9BUF7
[Other Products]
UniProt Related Accession #
Q9BUF7[Other Products]
NCBI Official Full Name
protein crumbs homolog 3 isoform a
NCBI Official Synonym Full Names
crumbs cell polarity complex component 3
NCBI Official Symbol
CRB3??[Similar Products]
NCBI Protein Information
protein crumbs homolog 3
UniProt Protein Name
Protein crumbs homolog 3
Protein Family
Protein crumbs
UniProt Gene Name
CRB3??[Similar Products]
UniProt Synonym Gene Names
UNQ588/PRO1158??[Similar Products]
UniProt Entry Name
CRUM3_HUMAN
NCBI Summary for CRB3
This gene encodes a member of the Crumbs family of proteins. This gene is widely expressed in epithelial tissues where the encoded protein isoforms play various roles such as the control of cytokinesis and ciliogenesis or the formation of tight junctions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Research Articles on CRB3
1. we report for the first time that CRB3 acts as an upstream regulator of the Hippo pathway to regulate contact inhibition by recruiting other Hippo molecules, such as Kibra and/or FRMD6, in mammary epithelial cells.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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