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Tripeptidyl Peptidase I (TPP1), ELISA Kit

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產品名稱: Tripeptidyl Peptidase I (TPP1), ELISA Kit
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Tripeptidyl Peptidase I (TPP1), ELISA Kit


Tripeptidyl Peptidase I (TPP1), ELISA Kit  的詳細介紹
Product Name

Tripeptidyl Peptidase I (TPP1), ELISA Kit

Full Product Name

Human Tripeptidyl Peptidase I (TPP1) ELISA Kit

Product Gene Name

TPP1 elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for O14773
Species Reactivity
Human
Preparation and Storage
Store at 2 to 8 degree C for 6 months.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of TPP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for TPP1 purchase
MBS160670 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tripeptidyl Peptidase I (TPP1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TPP1. The ELISA analytical biochemical technique of the MBS160670 kit is based on TPP1 antibody-TPP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TPP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TPP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TPP1. It may not necessarily be applicable to this product.
NCBI GI #
15928808
NCBI GeneID
1200
NCBI Accession #
AAH14863.1 [Other Products]
UniProt Primary Accession #
O14773 [Other Products]
UniProt Secondary Accession #
Q53HT1; Q5JAK6; Q6UX56; Q71JP6; Q96C37[Other Products]
UniProt Related Accession #
O14773[Other Products]
Molecular Weight
34,464 Da
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NCBI Official Full Name
Tripeptidyl peptidase I
NCBI Official Synonym Full Names
tripeptidyl peptidase 1
NCBI Official Symbol
TPP1??[Similar Products]
NCBI Official Synonym Symbols
CLN2; GIG1; LPIC; SCAR7; TPP-1
??[Similar Products]
NCBI Protein Information
tripeptidyl-peptidase 1
UniProt Protein Name
Tripeptidyl-peptidase 1
UniProt Synonym Protein Names
Cell growth-inhibiting gene 1 protein; Lysosomal pepstatin-insensitive protease; LPIC; Tripeptidyl aminopeptidase; Tripeptidyl-peptidase I; TPP-I
Protein Family
Tripeptidyl-peptidase
UniProt Gene Name
TPP1??[Similar Products]
UniProt Synonym Gene Names
CLN2; TPP-1; LPIC; TPP-I??[Similar Products]
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NCBI Summary for TPP1
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]
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UniProt Comments for TPP1
Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus ().
Research Articles on TPP1
1. The reports the crystal structure of the N-terminal domain of TIN2 in complex with TIN2-binding motifs from TPP1 and TRF2, revealing how TIN2 interacts cooperatively with TPP1 and TRF2.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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