Product Name
SLC26A4, Polyclonal Antibody
Full Product Name
SLC26A4 antibody - middle region
Product Gene Name
anti-SLC26A4 antibody
[Similar Products]
Product Synonym Gene Name
DFNB4; PDS; EVA; TDH2B[Similar Products]
Antibody/Peptide Pairs
SLC26A4 peptide (MBS3230970) is used for blocking the activity of SLC26A4 antibody (MBS3206008)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: ELNDRFRHKI PVPIPIEVIV TIIATAISYG ANLEKNYNAG IVKSIPRGFL
3D Structure
ModBase 3D Structure for O43511
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SLC26A4
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-SLC26A4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC26A4 antibody
This is a rabbit polyclonal antibody against SLC26A4. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3' of the S
Product Categories/Family for anti-SLC26A4 antibody
Polyclonal; Membrane Protein; Disease Related; Tissue Specific & Cell Marker; Immunohistochemistry;
Applications Tested/Suitable for anti-SLC26A4 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Immunohistochemistry (IHC) of anti-SLC26A4 antibody
Immunohistochemistry with Placenta tissue at an antibody concentration of 5ug/ml using anti-SLC26A4 antibody

Western Blot (WB) of anti-SLC26A4 antibody
Host: Rabbit
Target Name: SLC26A4
Sample Tissue: Human 786-0 Whole Cell
Antibody Dilution: 1ug/ml

Western Blot (WB) of anti-SLC26A4 antibody
Host: Rabbit
Target Name: SLC26A4
Sample Tissue: Human Ovary Tumor
Antibody Dilution: 1ug/ml

Western Blot (WB) of anti-SLC26A4 antibody
WB Suggested Anti-SLC26A4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysate

NCBI/Uniprot data below describe general gene information for SLC26A4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000432
[Other Products]
NCBI GenBank Nucleotide #
NM_000441
[Other Products]
UniProt Primary Accession #
O43511
[Other Products]
UniProt Related Accession #
O43511[Other Products]
NCBI Official Full Name
pendrin
NCBI Official Synonym Full Names
solute carrier family 26 member 4
NCBI Official Symbol
SLC26A4??[Similar Products]
NCBI Official Synonym Symbols
EVA; PDS; DFNB4; TDH2B
??[Similar Products]
NCBI Protein Information
pendrin
UniProt Protein Name
Pendrin
UniProt Synonym Protein Names
Sodium-independent chloride/iodide transporter; Solute carrier family 26 member 4
UniProt Gene Name
SLC26A4??[Similar Products]
UniProt Synonym Gene Names
PDS??[Similar Products]
NCBI Summary for SLC26A4
Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3' of the SLC26A3 gene. The encoded protein has homology to sulfate transporters. [provided by RefSeq, Jul 2008]
UniProt Comments for SLC26A4
Sodium-independent transporter of chloride and iodide.
Research Articles on SLC26A4
1. The present study suggests that the SLC26A4 gene plays a crucial role in the non-syndromic sensorineural hearing loss occurring in Iranian pedigrees and supports the specificity and unique spectrum of SLC26A4 variants among Iranian hearing loss patients.
Precautions
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Disclaimer
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