Product Name
Pendrin (SLC26A4), Recombinant Protein
Popular Item
Full Product Name
Recombinant Human Pendrin (SLC26A4), partial
Product Gene Name
SLC26A4 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
508-780. Partial.
Sequence
TVVLRVQFPS WNGLGSIPST DIYKSTKNYK NIEEPQGVKI LRFSSPIFYG NVDGFKKCIK STVGFDAIRV YNKRLKALRK IQKLIKSGQL RATKNGIISD AVSTNNAFEP DEDIEDLEEL DIPTKEIEIQ VDWNSELPVK VNVPKVPIHS LVLDCGAISF LDVVGVRSLR VIVKEFQRID VNVYFASLQD YVIEKLEQCG FFDDNIRKDT FFLTVHDAIL YLQNQVKSQE GQGSILETIT LIQDCKDTLE LIETELTEEE LDVQDEAMRT LAS
3D Structure
ModBase 3D Structure for O43511
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SLC26A4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SLC26A4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000432.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000441.1
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UniProt Primary Accession #
O43511
[Other Products]
UniProt Secondary Accession #
O43170; B7Z266[Other Products]
UniProt Related Accession #
O43511[Other Products]
Molecular Weight
39,267 Da
NCBI Official Full Name
pendrin
NCBI Official Synonym Full Names
solute carrier family 26 member 4
NCBI Official Symbol
SLC26A4??[Similar Products]
NCBI Official Synonym Symbols
EVA; PDS; DFNB4; TDH2B
??[Similar Products]
NCBI Protein Information
pendrin
UniProt Protein Name
Pendrin
UniProt Synonym Protein Names
Sodium-independent chloride/iodide transporter; Solute carrier family 26 member 4
UniProt Gene Name
SLC26A4??[Similar Products]
UniProt Synonym Gene Names
PDS??[Similar Products]
NCBI Summary for SLC26A4
Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3' of the SLC26A3 gene. The encoded protein has homology to sulfate transporters. [provided by RefSeq, Jul 2008]
UniProt Comments for SLC26A4
Sodium-independent transporter of chloride and iodide.
Research Articles on SLC26A4
1. Molecular analysis of human solute carrier SLC26A2, SLC26A3, and SLC26A4 anion transporter disease-causing mutations using 3-dimensional homology modeling has been presented.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
