Product Name
SLC9A3, Polyclonal Antibody
Full Product Name
SLC9A3 antibody - middle region
Product Gene Name
anti-SLC9A3 antibody
[Similar Products]
Product Synonym Gene Name
MGC126718; MGC126720; NHE3[Similar Products]
Antibody/Peptide Pairs
SLC9A3 peptide (MBS3232043) is used for blocking the activity of SLC9A3 antibody (MBS3207077)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: AEDMVTHHTL QQYLYKPRQE YKHLYSRHEL TPTEDEKQDR EIFHRTMRKR
3D Structure
ModBase 3D Structure for P48764
Species Reactivity
Cow, Dog, Human, Mouse, Pig, Rabbit, Rat, Sheep
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 77%; Dog: 92%; Human: 100%; Mouse: 92%; Pig: 77%; Rabbit: 77%; Rat: 92%; Sheep: 77%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SLC9A3
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-SLC9A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC9A3 antibody
This is a rabbit polyclonal antibody against SLC9A3. It was validated on Western Blot
Target Description: SLC9A3 is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. SLC9A3 is the major proton extruding system driven by the inward sodium ion chemical gradient. SLC9A3 plays an important role in signal transduction.
Product Categories/Family for anti-SLC9A3 antibody
Polyclonal; Ion Channel; Membrane & Traffic;
Applications Tested/Suitable for anti-SLC9A3 antibody
Western Blot (WB)
Western Blot (WB) of anti-SLC9A3 antibody
Host: Rabbit
Target Name: SLC9A3
Sample Tissue: Human RPMI-8226
Antibody Dilution: 1.0ug/ml
Western Blot (WB) of anti-SLC9A3 antibody
WB Suggested Anti-SLC9A3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: COLO205 cell lysate
NCBI/Uniprot data below describe general gene information for SLC9A3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004165
[Other Products]
NCBI GenBank Nucleotide #
NM_004174
[Other Products]
UniProt Primary Accession #
P48764
[Other Products]
UniProt Related Accession #
P48764[Other Products]
NCBI Official Full Name
sodium/hydrogen exchanger 3 isoform 1
NCBI Official Synonym Full Names
solute carrier family 9 member A3
NCBI Official Symbol
SLC9A3??[Similar Products]
NCBI Official Synonym Symbols
NHE3; DIAR8; NHE-3
??[Similar Products]
NCBI Protein Information
sodium/hydrogen exchanger 3
UniProt Protein Name
Sodium/hydrogen exchanger 3
UniProt Synonym Protein Names
Na(+)/H(+) exchanger 3
Protein Family
Sodium/hydrogen exchanger
UniProt Gene Name
SLC9A3??[Similar Products]
UniProt Synonym Gene Names
NHE-3??[Similar Products]
NCBI Summary for SLC9A3
The protein encoded by this gene is an epithelial brush border Na/H exchanger that uses an inward sodium ion gradient to expel acids from the cell. Defects in this gene are a cause of congenital secretory sodium diarrhea. Pseudogenes of this gene exist on chromosomes 10 and 22. [provided by RefSeq, Mar 2016]
UniProt Comments for SLC9A3
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient (PubMed:26358773). Plays an important role in signal transduction.
Research Articles on SLC9A3
1. We demonstrate that NHE3-799C is a common variant of NHE3 that is enriched in Asian populations; however its presence seems to have limited clinical significance in humans and is not associated with compromised function or abnormal transport regulation.
Precautions
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Disclaimer
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