Product Name
SLC9A3, Polyclonal Antibody
Full Product Name
SLC9A3 Antibody
Product Synonym Names
NHE3
Product Gene Name
anti-SLC9A3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P48764
Specificity
The antibody detects endogenous levels of total SLC9A3 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
0.5 mg/ml (lot specific)
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human Solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-SLC9A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SLC9A3 antibody
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.Binds SLC9A3R1 and SLC9A3R2. Interacts with CHP1, CHP2 and SHANK2. Interacts with PDZD3 and interactions decrease in response to elevated calcium ion levels
Product Categories/Family for anti-SLC9A3 antibody
Total protein Ab
Applications Tested/Suitable for anti-SLC9A3 antibody
Immunohistochemistry (IHC)
Application Notes for anti-SLC9A3 antibody
Immunohistochemistry: 1:25-1:100
Immunohistochemistry (IHC) of anti-SLC9A3 antibody
Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/20.
Immunohistochemistry (IHC) of anti-SLC9A3 antibody
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/20.
NCBI/Uniprot data below describe general gene information for SLC9A3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001271280.1
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NCBI GenBank Nucleotide #
NM_001284351.1
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UniProt Primary Accession #
P48764
[Other Products]
UniProt Secondary Accession #
Q3MIW3; B7ZKR2; E9PF67[Other Products]
UniProt Related Accession #
P48764[Other Products]
Molecular Weight
91,904 Da
NCBI Official Full Name
sodium/hydrogen exchanger 3 isoform 2
NCBI Official Synonym Full Names
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
NCBI Official Symbol
SLC9A3??[Similar Products]
NCBI Official Synonym Symbols
NHE3
??[Similar Products]
NCBI Protein Information
sodium/hydrogen exchanger 3
UniProt Protein Name
Sodium/hydrogen exchanger 3
UniProt Synonym Protein Names
Na(+)/H(+) exchanger 3
Protein Family
Sodium/hydrogen exchanger
UniProt Gene Name
SLC9A3??[Similar Products]
UniProt Synonym Gene Names
NHE-3??[Similar Products]
UniProt Entry Name
SL9A3_HUMAN
UniProt Comments for SLC9A3
NHE3: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. Binds SLC9A3R1 and SLC9A3R2. Interacts with SHANK2. Interacts with PDZD3 and interactions decrease in response to elevated calcium ion levels. Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Protein type: Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 5p15.3
Cellular Component: cell surface; brush border membrane; apical plasma membrane; integral to membrane; plasma membrane; brush border
Molecular Function: protein binding; sodium:hydrogen antiporter activity; PDZ domain binding
Biological Process: regulation of pH; ion transport; transmembrane transport
Research Articles on SLC9A3
1. the three NHE3 SNPs are unlikely to play a major role in the pathogenesis of SIDS in Caucasian infants;further genetic investigations in different ethnicities are required to determine whether variations in NHE3 are associated with an increased SIDS risk
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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