Full Product Name
SL9A3 Polyclonal Antibody
Product Synonym Names
Sodium/hydrogen exchanger 3; Na(+)/H(+) exchanger 3; NHE-3; Solute carrier family 9 member 3; SLC9A3; NHE3
Product Gene Name
anti-SL9A3 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P48764
Species Reactivity
Human, Rat
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Immunogen
Synthesized peptide derived from human protein. at AA range: 490-570
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-SL9A3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SL9A3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-SL9A3 antibody
WB: 1:500-2000
ELISA: 1:5000-20000
NCBI/Uniprot data below describe general gene information for SL9A3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001271280.1
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NCBI GenBank Nucleotide #
NM_001284351.2
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UniProt Primary Accession #
P48764
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UniProt Secondary Accession #
Q3MIW3; B7ZKR2; E9PF67[Other Products]
UniProt Related Accession #
P48764[Other Products]
NCBI Official Full Name
sodium/hydrogen exchanger 3 isoform 2
NCBI Official Synonym Full Names
solute carrier family 9 member A3
NCBI Official Symbol
SLC9A3??[Similar Products]
NCBI Official Synonym Symbols
NHE3; DIAR8; NHE-3
??[Similar Products]
NCBI Protein Information
sodium/hydrogen exchanger 3
UniProt Protein Name
Sodium/hydrogen exchanger 3
UniProt Synonym Protein Names
Na(+)/H(+) exchanger 3
UniProt Gene Name
SLC9A3??[Similar Products]
UniProt Synonym Gene Names
NHE-3??[Similar Products]
NCBI Summary for SL9A3
The protein encoded by this gene is an epithelial brush border Na/H exchanger that uses an inward sodium ion gradient to expel acids from the cell. Defects in this gene are a cause of congenital secretory sodium diarrhea. Pseudogenes of this gene exist on chromosomes 10 and 22. [provided by RefSeq, Mar 2016]
UniProt Comments for SL9A3
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient (PubMed:26358773). Plays an important role in signal transduction.
Research Articles on SL9A3
1. We demonstrate that NHE3-799C is a common variant of NHE3 that is enriched in Asian populations; however its presence seems to have limited clinical significance in humans and is not associated with compromised function or abnormal transport regulation.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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