Product Name
Kallikrein-15 (KLK15), Recombinant Protein
Full Product Name
Recombinant Human Kallikrein-15, Sf9
Product Synonym Names
Kallikrein Related Peptidase 15; ACO Protease; Kallikrein-Like Serine Protease; Kallikrein 15; Kallikrein-15; Prostinogen; EC 3.4.21.4; EC 3.4.21.-; EC 3.4.21; HSRNASPH; ACO; KLK15 Human, sf9; Kallikrein-15 Human Recombinant, sf9
Product Gene Name
KLK15 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ADP QDGDKLL EGDECAPHSQ PWQVALYERG RFNCGASLIS PHWVLSAAHC QSRFMRVRLG EHNLRKRDGP EQLRTTSRVI PHPRYEARSH RNDIMLLRLV QPARLNPQVR PAVLPTRCPH PGEACVVSGW GLVSHNEPGT AGSPRSQVSL PDTLHCANIS IISDTSCDKS YPGRLTNTMV CAGAEGRGAE SCEGDSGGPL VCGGILQGIV SWGDVPCDNT TKPGVYTKVC HYLEWIRETM KRNHHHHHH.
OMIM
AF242195 Genomic DNA
3D Structure
ModBase 3D Structure for Q9H2R5
Host
Sf9, Baculovirus cells
Purity/Purification
Greater than 80.0% as determined by SDS-PAGE
Form/Format
Sterile filtered colorless solution
Protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
Other Notes
Small volumes of KLK15 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
KLK15 recombinant protein
Description: KLK15 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 249 amino acids (17-256a.a.) and having a molecular mass of 27.4kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). KLK15 is expressed with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.
Introduction: Kallikrein-15 (KLK15) is one of the 15 kallikrein subfamily members located in a cluster on chromosome 19. KLK15 contains numerous polyadenylation sites and alternative splicing results in multiple transcript variants encoding different isoforms. KLK15 is over expressed in prostate cancer and therefore uses as a diagnostic or prognostic marker for prostate cancer.
Product Categories/Family for KLK15 recombinant protein
ENZYMES; Enzymes; Kallikrein; KLK15 Human, sf9
NCBI/Uniprot data below describe general gene information for KLK15. It may not necessarily be applicable to this product.
NCBI Accession #
Q9H2R5.1
[Other Products]
UniProt Primary Accession #
Q9H2R5
[Other Products]
UniProt Secondary Accession #
Q15358; Q6ISI0; Q9H2R3; Q9H2R4; Q9H2R6; Q9HBG9; A0AUY8[Other Products]
UniProt Related Accession #
Q9H2R5[Other Products]
Molecular Weight
28,016 Da
NCBI Official Full Name
Kallikrein-15
NCBI Official Synonym Full Names
kallikrein related peptidase 15
NCBI Official Symbol
KLK15??[Similar Products]
NCBI Official Synonym Symbols
ACO; HSRNASPH
??[Similar Products]
NCBI Protein Information
kallikrein-15
UniProt Protein Name
Kallikrein-15
UniProt Synonym Protein Names
ACO protease
Protein Family
Kallikrein
UniProt Gene Name
KLK15??[Similar Products]
NCBI Summary for KLK15
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for KLK15
Protease whose physiological substrate is not yet known.
Research Articles on KLK15
1. Pronounced correlations between KLK10/KLK11 (rs = 0.647) and between KLK9/KLK15 (rs = 0.716) mRNA, but not between other combinations, indicate coordinate expression of distinct pairs of peptidases
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
