For Research Use Only. Not for use in diagnostic procedures.

50 ug (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Appearance: Colorless liquid

0.5 mg/ml (lot specific)

At -20 degree C
Shelf Life: 12 months

Small volumes of Tgfbr2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

The peptide is used for blocking the antibody activity of TGF-beta Receptor II. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37 degree C.

64,241 Da[Similar Products]

transforming growth factor, beta receptor 2

TGF-beta receptor type-2

TGF-beta receptor type-2

TGFR-2; TGF-beta receptor type II; TbetaR-II??[Similar Products]

TGFR2_RAT

receptor for TGF-beta; may play a role in lung maturation and response to hypoxia [RGD, Feb 2006]

TGFBR2: a TKL kinase of the serine/threonine-protein kinase receptor (STKR) family. R1 and R2 TGF-beta receptors dimerize after binding TGF-beta at the cell surface. Binds to DAXX. Defects can cause esophageal cancer.

Protein type: Oncoprotein; Membrane protein, integral; EC 2.7.11.30; Protein kinase, TKL; Kinase, protein; Protein kinase, Ser/Thr (receptor); TKL group; STKR family; Type2 subfamily

Cellular Component: cell surface; integral to plasma membrane; cytoplasm; integral to membrane; caveola; cytosol; receptor complex; lipid raft; external side of plasma membrane

Molecular Function: glycosaminoglycan binding; protein homodimerization activity; metal ion binding; mitogen-activated protein kinase kinase kinase binding; transmembrane receptor protein serine/threonine kinase activity; transforming growth factor beta receptor activity; protein binding; transforming growth factor beta receptor activity, type II; transforming growth factor beta binding; protein heterodimerization activity; SMAD binding; ATP binding; receptor signaling protein serine/threonine kinase activity

Biological Process: lens development in camera-type eye; wound healing; apoptosis; positive regulation of smooth muscle cell proliferation; heart development; gastrulation; myeloid dendritic cell differentiation; palate development; positive regulation of tolerance induction to self antigen; protein amino acid phosphorylation; response to organic cyclic substance; response to organic substance; negative regulation of cell proliferation; negative regulation of cardiac muscle cell proliferation; transforming growth factor beta receptor signaling pathway; positive regulation of mesenchymal cell proliferation; transmembrane receptor protein serine/threonine kinase signaling pathway; response to glucose stimulus; positive regulation of NK T cell differentiation; vasculogenesis; response to nutrient; positive regulation of T cell tolerance induction; aging; response to drug; receptor-mediated endocytosis; smoothened signaling pathway; organ regeneration; positive regulation of skeletal muscle regeneration; embryonic hemopoiesis; in utero embryonic development; common-partner SMAD protein phosphorylation; peptidyl-threonine phosphorylation; embryonic cranial skeleton morphogenesis; regulation of cell proliferation; patterning of blood vessels; peptidyl-serine phosphorylation; positive regulation of angiogenesis; organ morphogenesis; gut development; response to estrogen stimulus; response to mechanical stimulus; regulation of gene expression; response to steroid hormone stimulus; positive regulation of B cell tolerance induction; cartilage development; response to hypoxia; activation of protein kinase activity; brain development; embryo implantation; lung development

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